Power spectra analysis following ceftriaxone administration.

<p><b>A.</b> Reduction in theta power at day 10. Waking mean absolute power spectra of Day 0 and Day 10 for frontal (above) and parietal (below) EEG channel. <b>B.</b> Power spectra analysis relative to the baseline illustrating a reduction of theta power at Day 10 (shown in detail for single animals in the small inset) and a return to the baseline eight days after CEF withdrawal (Day 16) in frontal (above) and parietal (below) EEG channels. Statistical significance (p<0.05) is represented by black dots. Values are mean ± sem. <b>C.</b> Time course analysis of relative spectra (7–9 Hz frequency band) showing a significant reduction of theta power for frontal and parietal channels two days (Day 10) and four days (Day 12) after CEF withdrawal compared to the baseline (Day 0). *p<0.05. Values are mean ± sem. <b>D.</b> Example of power spectrum relative to the baseline for a representative animal during the entire length of the experiment. <b>E.</b> Frontal and parietal relative spectra showing a broad band (7–13 Hz) reduction in power during NREM sleep at day 10. Statistical significance (p<0.05) is represented by black dots. Values are mean ± sem. <b>F.</b> Frontal and parietal relative spectra showing a reduction in theta power during REM sleep at day 10. Statistical significance (p<0.05) is represented by black dots. Values are mean ± sem.