Different expression of ECM in uPAR−/− nerves after damage.

<p>Sciatic nerve cryosections from Wt (A, C, E, G, I, K) and uPAR−/− (B, D, F, H, J, L) mice stained for fibrin (Fg), fibronectin (Fn) or vitronectin (Vn), and neurofilaments (Nf) at 15 and 45 dpc. Both at 15 and 45 dpc Fibrin expressions was higher in uPAR−/− as compared to Wt endoneurium (B versus A, and H versus G). Fibronectin expression was similarly in Wt and uPAR−/− mice at both time points (D versus C, and J versus I). Vitronectin expression was higher in uPAR−/− mice as compared to wt at 15dpc (F versus E), whereas it was similar at 45 dpc (L and K). Bar = 50 µm.