Schwann cell IR and remyelination in the injured sciatic nerve.

<p>At 13 days after SNC, we measured S100 (left column) and myelin basic protein (MBP, middle column) IR immediately proximal and distal to the lesion site. The distal/proximal ratio for both S100 and MBP IR was reduced. For S100, this decrease was more prominent in <i>GFAP^–/–Vim^–/–</i> mice (B, column one) than in WT mice (A), quantified in (C). We observed a decrease in MBP IR ratio both for WT and <i>GFAP^–/–Vim^–/–</i> mice but did not detect any difference between the two groups of mice (D). Error bars indicate SEM. *p<0.05 (one-way ANOVA), ns = non-significant. Scale bar, 50 µm.