Protection of mice against pathogenic vaccinia VTT strain challenge.

<p>Groups of ten BALB/c mice (3-week-old) were vaccinated with 5×10⁴ PFU MVTT1, MVTT2 or MVTT3 via intramuscular routes. Mice received PBS were included as controls. Four weeks post-immunization, the mice were challenged intranasally with 500×LD₅₀ VTT strain. Cross marks indicate the mice that were killed because of a 30% weight loss. Data show average percent change in pre-challenge weigh. The error bar indicates the standard deviation (SD) of animals from each group.