Protection of mice from vaccinia WR or IHD-J challenge.

<p>Mice (groups of 5) were mock-immunized with PBS or immunized with either 10³ or 10⁵ pfu of A33R/B5Rko virus or DV-3. Mice were challenged intranasally with 25 LD₅₀ of either vaccinia WR (A) or IHD-J (B) and were observed for 10 days for weight loss and lethality. The mean percentage change in body weight in each group is shown. Data are representative of two identical challenge experiments. The results of all challenge experiments are presented in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0067984#tab1" target="_blank">Tables 1</a> and <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0067984#tab2" target="_blank">2</a>.