Expression and close proximity of CD44 and CD155 on GBM cells.

<p><b>a–c</b>, Co-staining of CD44 (red) and CD155 (green) on SNB-19 and UPAB cells; scale bars: 25 µm (<b>a</b>) and 10 µm (<b>b</b>–<b>c</b>). TIRF microscopy (<b>c</b>) clearly demonstrated the juxtaposition of CD44 and CD155. CD155 is mainly expressed on the processes and invadapodia (arrows). <b>d</b>, Significantly increased expression of CD44 (<b>top panel</b>) and CD155 (<b>bottom panel</b>) in GBM cells confirmed by flow cytometry, as assessed by the percentage of antigen-expressing cells and increase in fluorescence fold. * indicates statistical significance compared to CC-2565, a normal human astrocyte cell line.