Induction of MSP1-specific IL-4 (grey bars) and IFN-γ (white bars) responses, as determined by ELISPOT, in mice immunized with truncated MSP1-42 proteins.

<p>Panel A: Constructs 33-A – 33-D; Panel B: Constructs 33-E – 33-K. Horizontal bars indicate mean SFU. Logistic Regression for Repeated Measures indicated that IFNγ levels were significantly higher (p<0.05) in Construct 33-E – 33-K compared to Construct 33-A – 33-D. No significant difference was found when comparing IL-4 levels. Mouse splenocytes were harvested 21 days after the last immunization.