LBP pre-treatment lowered lipid peroxidation but not nitrosative stress in I/R retina.

<p>(A–C) Immunohistochemisty of poly(ADP-ribose) (PAR). PAR expression was localized in the cytosol of cells of the non-ischemic control retina and LBP-treated I/R retina (arrow heads in A & C). However, PAR expression was found inside the cell nuclei of the vehicle-treated retina (arrow in B). (D–F) Immunohistochemistry of nitrotyrosine (NT). A minimal NT expression was seen in the non-ischemic control retina (D). However, an increased level of NT immunoreactivity was noted in the vehcle-treated I/R retina and LBP-treated I/R retina (E & F). Results were confirmed by semi-quantification of IHC (G, PAR; H, NT). ^#p<0.05 vs. non-ischemic control retina; *P<0.05 vs. vehicle-treated I/R retina. Scale bar, 25 µm.