Real-time RT-PCR validation of dysregulated miRNA expression.

<p>(A) The graphs show miRNAs that were significantly upregulated in splenocytes from MRL-lpr and B6-lpr mice when compared to control MRL and B6 mice, respectively. (B) The graph shows miRNAs that are upregulated in both purified splenic B and T cells from MRL-lpr when compared to MRL mice. The graphs represent the means ± SEMs (n = 4 each). Student <i>t</i>-tests were performed. *, **, and *** indicate <i>p</i><0.05, <i>p</i><0.01, and <i>p</i><0.001, respectively.