<p>(A) Apoptosis induced by knocking down PTK7 was caspase-dependent. Data are mean±s.d. of three independent experiments. *Student's t-test: P<0.05. (B) Caspase-10 inhibitor totally blocked the apoptosis induced by knock down of PTK7. Data: mean±s.d. of three independent experiments, *Student's t-test: P<0.05.</p
<p>Western blotting assay was used to analyze the activation of caspases in Kasumi-1 cells treated w...
<p>(A) Flow cytometry assay for the binding of the PE-labeled anti-PTK7 with HCT 116 cells (Grey cur...
<p>(A–C) The lung carcinoma cell line H1299 and the osteosarcoma cell line HOS were transfected with...
<p>(A) Western blot analysis of procaspase-10 and Bid in HCT 116 cells transfected by PTK7 siRNAs. T...
<p>(A) Flow cytometry assay for the binding of the PE-labeled anti-PTK7 with p53-null HCT 116 cells ...
<p>(A) Cell-cycle-related protein expressions with siRNA treatment. (B) The percentage of apoptotic ...
<p>No significant effect of Caspases inhibitors on cell viability was observed by MTT (A). Apoptosis...
<p>ER-dnE2F1 cells were transfected with siRNA specific for PTP-1B (+PTP-1B), SHP-2 (+SHP-2), or PTE...
<p>(A–F) HeLa cells were transfected with control non-targeting siRNA (A, D), PTPMT1 siRNA#1 (B, E),...
<p>(A) HeLa cells were transfected with a dose response of non-targeting (blue line), PTPMT1#1 (gree...
<p>RT112 and T24 cells were treated with RAD001 (5 nM), NVP-BEZ235 (100 nM for T24, 500 nM for RT112...
<p>(A,B) Cells were transfected with TASK-1 siRNA or non-silencing siRNA (control siRNA). 48 hours a...
<p>(A) Fluorescence microscope detection of mitochondrial membrane potential in treated HCT 116 cell...
<p>A. Apoptosis induced by JD or/with Caspase-8 inhibitor (Z-IETD-FMK) or Caspase-9 inhibitor (Z-LEH...
<p>KTC-1 cells were left untreated as controls (<b>A</b>), or treated with 20 MBq/ml <sup>131</sup>I...
<p>Western blotting assay was used to analyze the activation of caspases in Kasumi-1 cells treated w...
<p>(A) Flow cytometry assay for the binding of the PE-labeled anti-PTK7 with HCT 116 cells (Grey cur...
<p>(A–C) The lung carcinoma cell line H1299 and the osteosarcoma cell line HOS were transfected with...
<p>(A) Western blot analysis of procaspase-10 and Bid in HCT 116 cells transfected by PTK7 siRNAs. T...
<p>(A) Flow cytometry assay for the binding of the PE-labeled anti-PTK7 with p53-null HCT 116 cells ...
<p>(A) Cell-cycle-related protein expressions with siRNA treatment. (B) The percentage of apoptotic ...
<p>No significant effect of Caspases inhibitors on cell viability was observed by MTT (A). Apoptosis...
<p>ER-dnE2F1 cells were transfected with siRNA specific for PTP-1B (+PTP-1B), SHP-2 (+SHP-2), or PTE...
<p>(A–F) HeLa cells were transfected with control non-targeting siRNA (A, D), PTPMT1 siRNA#1 (B, E),...
<p>(A) HeLa cells were transfected with a dose response of non-targeting (blue line), PTPMT1#1 (gree...
<p>RT112 and T24 cells were treated with RAD001 (5 nM), NVP-BEZ235 (100 nM for T24, 500 nM for RT112...
<p>(A,B) Cells were transfected with TASK-1 siRNA or non-silencing siRNA (control siRNA). 48 hours a...
<p>(A) Fluorescence microscope detection of mitochondrial membrane potential in treated HCT 116 cell...
<p>A. Apoptosis induced by JD or/with Caspase-8 inhibitor (Z-IETD-FMK) or Caspase-9 inhibitor (Z-LEH...
<p>KTC-1 cells were left untreated as controls (<b>A</b>), or treated with 20 MBq/ml <sup>131</sup>I...
<p>Western blotting assay was used to analyze the activation of caspases in Kasumi-1 cells treated w...
<p>(A) Flow cytometry assay for the binding of the PE-labeled anti-PTK7 with HCT 116 cells (Grey cur...
<p>(A–C) The lung carcinoma cell line H1299 and the osteosarcoma cell line HOS were transfected with...