SSZ promotes a TH2 cytokine environment during PcP-related IRIS.

<p>Pc-infected SCID mice were immunologically reconstituted, and then treated with PBS or SSZ. (A) IL-4 levels and (B) IL-4/IFN-γ ratios were measured in the lung homogenates of experimental mice at indicated time points. Values are mean ±1 SEM (n≥10/time point/group). *, P<0.05 as compared to PBS treated mice at the same time point. Mean represents combined data from five independent experiments.