<p>Infection with purified HCP, wild-type O157:H7 and the <i>hcpA</i> mutant showing percentages of AP-1 activation; PMA: Phorbol myristate acetate (A). Infection with purified HCP, wild-type O157:H7 and the <i>hcpA</i> mutant showing percentages of NF-κB activation (B). Western blot showing the kinetics of MAPK activation using specific antibodies that recognize the phosphorylated forms of p42 and p44 (C). Wild-type EHEC is involved in the p38 phosphorylation in conditions where HCP is produced and a significant decrease was observed when tested with the EDL933 <i>hcpA</i> mutant (D). ERK1/2 and JNK activation were detectable after 3 h of EHEC infection (E). IκB-α activation was detectable after 3 h of EHEC infection (F). * EDL933 O157:H7 ...
<p>(A) Alignment of OspE2 homologs EspO1-1 and EspO1-2 in EHEC strain Sakai. EspO1-1 and EspO1-2 hav...
<p>(A) HKM were transfected with PKACA-siRNA, scrambled siRNA or pre-treated with H-89, U 0126 then ...
<p>(A) Strains were grown on enterohemolysin agar for 24 h at 37°C and the plates were examined for ...
<p>CagA and activated MAPK (ERK2) expression in <i>hcp</i> mutants, WT G27MA and uninfected AGS cell...
<p>(A) HF cells were mock-infected (-) or infected (+) with HCMV (Towne) at an MOI of 2 IFU per cell...
<p>Western blot analysis was performed to assess the levels of phosphorylated p38 MAPK (phospho-p38)...
<p>(<b>A, B</b>) HBMEC (<b>A</b>) and Caco-2 cells (<b>B</b>) were incubated with different doses of...
<p>HeLa cells were serum-starved for 16 h prior to infection with preactivated EPEC for 1, 2 or 3 h ...
<p>(<b>A</b>) Western blot showing the protein levels of HIF-1α, p53, phosphorylated ERK 1/2 (P-MAPK...
<p>Growth factor-starved primary HCECs cells were either left unchallenged (CT) or challenged with p...
<p>(A) Analysis of H3S10p in HCMV infected HFF cells treated with BAY61-3606. HFF cells were uninfec...
<p>BMMΦs were mock infected or infected at an MOI of 1 with MCMV, MCMVdie1 or MCMVrev (n = 3). (A) W...
<p>(<b>A</b>) Western blot analyses of HCT116 cells infected for 24, 48, or 72 hrs and analyzed with...
<p><b>A.</b> J774.A1 and RAW 264.7 cells rapidly phosphorylate JNK 1/2 in response to X-31 exposure....
<p>(A) HeLa cells were infected with Δ<i>espO1-1</i>Δ<i>espO1-2</i> carrying pK19-HA or Δ<i>espO1-1<...
<p>(A) Alignment of OspE2 homologs EspO1-1 and EspO1-2 in EHEC strain Sakai. EspO1-1 and EspO1-2 hav...
<p>(A) HKM were transfected with PKACA-siRNA, scrambled siRNA or pre-treated with H-89, U 0126 then ...
<p>(A) Strains were grown on enterohemolysin agar for 24 h at 37°C and the plates were examined for ...
<p>CagA and activated MAPK (ERK2) expression in <i>hcp</i> mutants, WT G27MA and uninfected AGS cell...
<p>(A) HF cells were mock-infected (-) or infected (+) with HCMV (Towne) at an MOI of 2 IFU per cell...
<p>Western blot analysis was performed to assess the levels of phosphorylated p38 MAPK (phospho-p38)...
<p>(<b>A, B</b>) HBMEC (<b>A</b>) and Caco-2 cells (<b>B</b>) were incubated with different doses of...
<p>HeLa cells were serum-starved for 16 h prior to infection with preactivated EPEC for 1, 2 or 3 h ...
<p>(<b>A</b>) Western blot showing the protein levels of HIF-1α, p53, phosphorylated ERK 1/2 (P-MAPK...
<p>Growth factor-starved primary HCECs cells were either left unchallenged (CT) or challenged with p...
<p>(A) Analysis of H3S10p in HCMV infected HFF cells treated with BAY61-3606. HFF cells were uninfec...
<p>BMMΦs were mock infected or infected at an MOI of 1 with MCMV, MCMVdie1 or MCMVrev (n = 3). (A) W...
<p>(<b>A</b>) Western blot analyses of HCT116 cells infected for 24, 48, or 72 hrs and analyzed with...
<p><b>A.</b> J774.A1 and RAW 264.7 cells rapidly phosphorylate JNK 1/2 in response to X-31 exposure....
<p>(A) HeLa cells were infected with Δ<i>espO1-1</i>Δ<i>espO1-2</i> carrying pK19-HA or Δ<i>espO1-1<...
<p>(A) Alignment of OspE2 homologs EspO1-1 and EspO1-2 in EHEC strain Sakai. EspO1-1 and EspO1-2 hav...
<p>(A) HKM were transfected with PKACA-siRNA, scrambled siRNA or pre-treated with H-89, U 0126 then ...
<p>(A) Strains were grown on enterohemolysin agar for 24 h at 37°C and the plates were examined for ...