Indirect ELISA measuring RVFV specific IgG responses in mice immunized with indicated vaccine regimens.

<p>All groups received primary and two booster immunizations (except MP12) spaced 3 weeks apart. Serum samples were collected two weeks after the last immunization (week 8 of the study), except for group of mice vaccinated at week 0 with MP12 (MP12.wk0) which was challenged 8 weeks post-vaccination. End point dilution titers were conducted by diluting the sera until the OD values reached the background levels. Each dot represents an individual mouse. Error bars denote the standard error within the samples with a measurable titer. Representative data from 1 of 2 experiments shown. A 1-way ANOVA with Tukey's multiple comparison test was used to determine the significance of the data between groups, which is denoted by asterisks; *** p<0.001 for both MP12 vaccine regimens compared to the other vaccine regimens.