Different staining patterns of NMO-IgG in M-1 and M-23 AQP4 transfected cells.
- Simone Mader (365012)
- Andreas Lutterotti (89552)
- Franziska Di Pauli (365013)
- Bettina Kuenz (89551)
- Kathrin Schanda (365014)
- Fahmy Aboul-Enein (351477)
- Michael Khalil (365015)
- Maria K. Storch (365016)
- Sven Jarius (25658)
- Wolfgang Kristoferitsch (351482)
- Thomas Berger (72614)
- Markus Reindl (89559)
Publication date
February 2013
DOIAbstract
<p>Anti-AQP4 IgG (red) in NMO patient's serum targets AQP4 (green), which is expressed by transiently transfected HEK cells. Performing the assay for M-23 AQP4 (<b>A</b>, green) versus M-1 AQP4 (<b>B</b>, green), results in different staining patterns of NMO-IgG (red). Weaker binding was observed to M-1 AQP4, which contrary to M-23 AQP4 forms only few orthogonal arrays of particles.</p
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