Enrichment of cancer genes in SSM-prone genes.
- Christy L. Rhine (4911415)
- Kamil J. Cygan (4911412)
- Rachel Soemedi (610265)
- Samantha Maguire (4911421)
- Michael F. Murray (4911418)
- Sean F. Monaghan (4911424)
- William G. Fairbrother (194896)
Publication date
March 2018
DOIAbstract
<p><b>A.</b> SSM versus all exonic mutations in the HGMD with regions of 99.9% confidence interval shown in gray. COSMIC cancer genes are highlighted in Red. <i>MLH1</i>, <i>BRCA1</i>, <i>BRCA2</i>, and <i>NF1</i> are highlighted and labeled. <b>B-C.</b> Average percent of SSM or ESM in cancer genes versus non-cancer genes reported in HGMD. <b>D.</b> Average HI score of cancer genes in Upper, Expected, and Lower categories of genes.</p
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