Loss of heterozygosity events are more common in tumor suppressor genes.
- David M. Vossen (5946188)
- Caroline V. M. Verhagen (5946191)
- Reidar Grénman (4599841)
- Roelof J. C. Kluin (5946194)
- Marcel Verheij (821771)
- Michiel W. M. van den Brekel (5220671)
- Lodewyk F. A. Wessels (80241)
- Conchita Vens (5946197)
Publication date
November 2018
DOI Publisher
Public Library of Science (PLoS)Abstract
(A) The percentage of HNSCC samples with LOH per TSG (dark red) and OG (dark blue). HNSCC TSG and oncogenes (OG) are as reported by Leemans et al. Light colors represent the percentage of samples without LOH (wt). Fraction of samples with LOH are indicated by numbers and dark colors. (B) Boxplot representation of the percentage of HNSCC tumor samples with LOH in any TSGs or OGs as shown in Fig 3A. TSGs are enriched for LOH events (p<0.005).</p
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