<p>Data are presented as average ± S.E.M.</p><p>*: denotes <i>P</i><0.016 compared to perfused fibers under identical experimental conditions.</p><p>†: denotes <i>P</i><0.016 compared to perfused and reperfused fibers under identical experimental conditions.</p><p>‡: denotes <i>P</i><0.016 compared to perfused and ischemic fibers under identical experimental conditions.</p
<p>pCa<sub>50</sub>, pCa required for generation of 50% of maximal force. <i>n</i>, number of skinne...
<div><p>(A) No differences were seen in total force generation in isolated muscle fibers. Mechanical...
<p>(<b>A</b>) In the Ca<sup>2+</sup>-force relationship, the Ca<sup>2+</sup>-sensitivity of isometri...
<p>(A) Force per cross-sectional area versus Ca<sup>2+</sup> concentration for perfused (•), ischemi...
<p>(A) Typical force transients from representative perfused, ischemic and ischemia-reperfused fiber...
<p>(A) Sample records from a typical experiment showing superimposed contractions produced by a fibr...
<p>(A) The rate constant of force redevelopment at various [Pi] for perfused (circles) and ischemic ...
<p>P<sub>r</sub>/P<sub>0</sub>, force expressed relative to maximal Ca<sup>2+</sup>-activated force,...
<p>(A) Superimposed contractions showing the force increase during stretch while the fibre was activ...
<p>(A) Superimposed contractions showing the force decrease during shortening while the fiber was ac...
<p>(A) Representative traces of force after length release for a perfused fiber activated by pCa4.5 ...
<p>(A) Typical force transients from a representative perfused and ischemic fiber activated from Ca<...
<p>Panel A shows the mean (±SD) of peak Ca<sup>2+</sup> flux in fibers of healthy volunteers (hatche...
<p>Force was generated in response to incubation with incremental increase of [Ca<sup>2+</sup>]. Not...
<p>Maximal isometric steady-state force generation was significantly lower in Tg(<i>TPM3</i>)<sup>Me...
<p>pCa<sub>50</sub>, pCa required for generation of 50% of maximal force. <i>n</i>, number of skinne...
<div><p>(A) No differences were seen in total force generation in isolated muscle fibers. Mechanical...
<p>(<b>A</b>) In the Ca<sup>2+</sup>-force relationship, the Ca<sup>2+</sup>-sensitivity of isometri...
<p>(A) Force per cross-sectional area versus Ca<sup>2+</sup> concentration for perfused (•), ischemi...
<p>(A) Typical force transients from representative perfused, ischemic and ischemia-reperfused fiber...
<p>(A) Sample records from a typical experiment showing superimposed contractions produced by a fibr...
<p>(A) The rate constant of force redevelopment at various [Pi] for perfused (circles) and ischemic ...
<p>P<sub>r</sub>/P<sub>0</sub>, force expressed relative to maximal Ca<sup>2+</sup>-activated force,...
<p>(A) Superimposed contractions showing the force increase during stretch while the fibre was activ...
<p>(A) Superimposed contractions showing the force decrease during shortening while the fiber was ac...
<p>(A) Representative traces of force after length release for a perfused fiber activated by pCa4.5 ...
<p>(A) Typical force transients from a representative perfused and ischemic fiber activated from Ca<...
<p>Panel A shows the mean (±SD) of peak Ca<sup>2+</sup> flux in fibers of healthy volunteers (hatche...
<p>Force was generated in response to incubation with incremental increase of [Ca<sup>2+</sup>]. Not...
<p>Maximal isometric steady-state force generation was significantly lower in Tg(<i>TPM3</i>)<sup>Me...
<p>pCa<sub>50</sub>, pCa required for generation of 50% of maximal force. <i>n</i>, number of skinne...
<div><p>(A) No differences were seen in total force generation in isolated muscle fibers. Mechanical...
<p>(<b>A</b>) In the Ca<sup>2+</sup>-force relationship, the Ca<sup>2+</sup>-sensitivity of isometri...