c<p>Data from individual activation curves obtained from 5–10 oocytes. Activation curves were fit to a Boltzmann function. V<sub>½</sub> is the voltage of half-maximal activation and <i>z</i> is the slope factor. ΔV<sub>1/2</sub> and Δ <i>z</i> are the changes induced by addition of 10 mM PBA. All values are mean±SEM.</p>*<p>Indicates significant (Student <i>t</i>-test; p<0.05) when compared to K<sup>+</sup>.</p
<p>(A) Average peak currents normalized to cell capacitance. Smooth curves represent fits to the ave...
<p><i>A.</i> I<sub>to</sub> traces recorded in a representative cell with the voltage protocol showe...
<p>The graphs show the membrane potential of the PG cell model in response to a depolarizing current...
<p><b>A</b>, illustrates half-activation voltages (V<sub>50</sub>) of currents resulting from expres...
<p>(A) Whole-cell current traces from representative experiments of WT-Q1077del and S1787N/Q1077del ...
<p> = 5–9, *<i>P</i><0.05, **<i>P</i><0.01, ***<i>P</i><0.001). Values were obtained from mean data ...
<p>Aa shows representative raw traces were elicited by a series of voltage champs from a holding pot...
<p>(A) Concentration response curves for ATP in <i>Lym</i>P2X expressing oocytes. Mean peak currents...
<p>A. Current traces for ciHCNa (above) and ciHCNb (below), elicited by the staggered voltage protoc...
<p>The <i>G<sub>max</sub></i> and <i>V<sub>0.5</sub></i> of activation were determined from the <i>I...
<p>(A) Time course of Q1/E3 current measured in ND96 at +40 mV at the end of a 2 s pulse. The curren...
<p>Current traces were recorded in (A) 50 mM K<sup>+</sup>, (B) Rb<sup>+</sup>, or (C) Cs<sup>+</sup...
<p><b>(A)</b> Action potential amplitude and <b>(B)</b> resting membrane potential between control (...
<p>For the compound outward current in male and female wild-type (KChIP2<sup>+/+</sup>) myocytes the...
<p>The activation and inactivation gating variables for each of the 7 active membrane conductances u...
<p>(A) Average peak currents normalized to cell capacitance. Smooth curves represent fits to the ave...
<p><i>A.</i> I<sub>to</sub> traces recorded in a representative cell with the voltage protocol showe...
<p>The graphs show the membrane potential of the PG cell model in response to a depolarizing current...
<p><b>A</b>, illustrates half-activation voltages (V<sub>50</sub>) of currents resulting from expres...
<p>(A) Whole-cell current traces from representative experiments of WT-Q1077del and S1787N/Q1077del ...
<p> = 5–9, *<i>P</i><0.05, **<i>P</i><0.01, ***<i>P</i><0.001). Values were obtained from mean data ...
<p>Aa shows representative raw traces were elicited by a series of voltage champs from a holding pot...
<p>(A) Concentration response curves for ATP in <i>Lym</i>P2X expressing oocytes. Mean peak currents...
<p>A. Current traces for ciHCNa (above) and ciHCNb (below), elicited by the staggered voltage protoc...
<p>The <i>G<sub>max</sub></i> and <i>V<sub>0.5</sub></i> of activation were determined from the <i>I...
<p>(A) Time course of Q1/E3 current measured in ND96 at +40 mV at the end of a 2 s pulse. The curren...
<p>Current traces were recorded in (A) 50 mM K<sup>+</sup>, (B) Rb<sup>+</sup>, or (C) Cs<sup>+</sup...
<p><b>(A)</b> Action potential amplitude and <b>(B)</b> resting membrane potential between control (...
<p>For the compound outward current in male and female wild-type (KChIP2<sup>+/+</sup>) myocytes the...
<p>The activation and inactivation gating variables for each of the 7 active membrane conductances u...
<p>(A) Average peak currents normalized to cell capacitance. Smooth curves represent fits to the ave...
<p><i>A.</i> I<sub>to</sub> traces recorded in a representative cell with the voltage protocol showe...
<p>The graphs show the membrane potential of the PG cell model in response to a depolarizing current...