Renal function, injury and inflammatory influx in wild type, MyD88−/− and TRIF-mutant mice.

<p>Renal function of MyD88−/− and TRIF-mutant mice (black bars) did not differ compared with that of their wild type mice (white bars) one day after renal I/R as reflected by serum urea (A) and creatinine (B) levels and tubular injury (C). In addition, no differences were observed in the number of infiltrating granulocytes in kidneys of MyD88−/− and TRIF-mutant mice compared with their wild type mice (D). Data are mean±SEM of 6 (TRIF) or 8 (MyD88) mice per group (sham-operated animals: n = 2/group (TRIF) or n = 3/group (MyD88)). * p<0.05.