Scoring renal tubular damage of wild type and TLR4−/− mice.

<p>Score for histopathology after renal I/R injury (A) using PAS-D-stained renal tissue sections (B; representative for t = 1). Tubular damage was significantly lower in the outer medulla of kidneys of TLR4−/− mice (black bars) than in kidneys of wild type mice (white bars) one day after I/R injury. Data are mean±SEM of 8 mice per group (sham-operated animals: n = 3/group). * p<0.05.