Heterochromatin exclusion from replication compartments during HSV-1 infection requires lamin A/C.

<p><i>Lmna^+/+</i> and <i>Lmna^−/−</i> MEFs were either mock-infected or infected with HSV-1 at an MO of 20, fixed at 8 hpi, and stained with antibodies against ICP8 (green) and either trimethyl H3K9 (Panel A; red), trimethyl H4K20 (panel B; red), or heterochromatin protein 1α (panel C; red).