a<p>Calculations were as followed: for each mouse, the ratio between type III and type I IFN transcripts (IFN-λ/IFN-α or IFN-λ/IFN-β was calculated for the liver and for the brain. Mean ratios were then calculated for liver samples and for brain samples.</p>b<p>Mann-Whitney p values testing whether the mean ratio between type III and type I expression measured in the liver differs significantly from that measured in the brain.</p
<p>Flow cytometric analysis of the (A) frequency of IFN-α-positive spleen cells and (B) mean fluores...
(A-B) Human colon organoids were stimulated with indicated concentrations of type I (β) or III IFN (...
<p><b>A:</b> Fluorescence microscopy images showing the IFN response (Mx1, green) in hepatocytes (HN...
<p>Histograms show the number of IFN cDNA copies per 10<sup>6</sup> β-actin cDNA copies, determined ...
<p>A) Serum cytokine concentration of IFNγ in infected C57BL/6 mice. Values represent mean ± SD of 4...
<p>(<b>A</b>) Experimental schedule in chimeric mice infected with HCV. (<b>B</b>) Serum concentrati...
<p>IFN-α coding sequences were amplified by RT-PCR using a primer mixture designed to amplify equall...
<p>Two representative mice from four independent transgenic HyBNAR strains were injected IV. with 40...
<p>We infected chimeric mice produced with hepatocytes from donor Hu8063 with either HCVgt1a or HCVg...
<p>Expression levels of (A) IFN-γ, (B) COX-2, and (C) TNF-α mRNA in hepatic tumors and in normal liv...
<p>IFN-β concentration in the (A) liver, (B) spleen, and (C) brain in mice after infection. The firs...
<p>Antagonist activity in mice was determined by their ability to induce or inhibit IFN-induced gene...
<p><b>A</b> and <b>B</b>. The expression of type I IFNs (IFN-α and β) in lymphoid and inflammatory t...
<p>Values are means ± SEM for A and B. (a) FASD mice (grey bar; 3 experiments combined; n = 10) had ...
<p>Expression of IFN-α4, IFN-β1, OAS2, IFIT-1, IFIT-2 and IRF-7 mRNA relative to the housekeeping ge...
<p>Flow cytometric analysis of the (A) frequency of IFN-α-positive spleen cells and (B) mean fluores...
(A-B) Human colon organoids were stimulated with indicated concentrations of type I (β) or III IFN (...
<p><b>A:</b> Fluorescence microscopy images showing the IFN response (Mx1, green) in hepatocytes (HN...
<p>Histograms show the number of IFN cDNA copies per 10<sup>6</sup> β-actin cDNA copies, determined ...
<p>A) Serum cytokine concentration of IFNγ in infected C57BL/6 mice. Values represent mean ± SD of 4...
<p>(<b>A</b>) Experimental schedule in chimeric mice infected with HCV. (<b>B</b>) Serum concentrati...
<p>IFN-α coding sequences were amplified by RT-PCR using a primer mixture designed to amplify equall...
<p>Two representative mice from four independent transgenic HyBNAR strains were injected IV. with 40...
<p>We infected chimeric mice produced with hepatocytes from donor Hu8063 with either HCVgt1a or HCVg...
<p>Expression levels of (A) IFN-γ, (B) COX-2, and (C) TNF-α mRNA in hepatic tumors and in normal liv...
<p>IFN-β concentration in the (A) liver, (B) spleen, and (C) brain in mice after infection. The firs...
<p>Antagonist activity in mice was determined by their ability to induce or inhibit IFN-induced gene...
<p><b>A</b> and <b>B</b>. The expression of type I IFNs (IFN-α and β) in lymphoid and inflammatory t...
<p>Values are means ± SEM for A and B. (a) FASD mice (grey bar; 3 experiments combined; n = 10) had ...
<p>Expression of IFN-α4, IFN-β1, OAS2, IFIT-1, IFIT-2 and IRF-7 mRNA relative to the housekeeping ge...
<p>Flow cytometric analysis of the (A) frequency of IFN-α-positive spleen cells and (B) mean fluores...
(A-B) Human colon organoids were stimulated with indicated concentrations of type I (β) or III IFN (...
<p><b>A:</b> Fluorescence microscopy images showing the IFN response (Mx1, green) in hepatocytes (HN...