Average position-specific hydrophobicity in 25-residue fragments containing the central PEXEL motif (at positions 11-15).

<p>Color indicates the protein family (black: PfEMP1, gray: RIFIN, light gray: STEVOR). Error bars give standard deviations. Asterisks indicate positions characteristic for one of the families. Note that the Hopp & Woods scale <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0001560#pone.0001560-Hopp1" target="_blank">[20]</a> is a “hydrophilicity” scale with negative values for hydrophobic residues.