Hydrophobicity of Trigger factor.

<p>(<b>A</b>) Standard hydrophobicity of TF per residue <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0059683#pone.0059683-Monera1" target="_blank">[48]</a>, plotted as a coloured-barcode. The hydrophobicity scale varies from red – very hydrophilic (viz. ) – to green – very hydrophobic (viz. ). White-coloured residues are more likely to be hydrophobic than hydrophilic. (<b>B</b>) Standard hydrophobicity of TF residues, sequentially-averaged over groups of 5 residues. On the same hydrophobicity scale, hydrophobicity maps obtained from averaged (over 4 MD runs of 30 ns each) probability histograms of binding of hydrophobic probes to TF are also plotted, (<b>C</b>) in the extended conformation, (<b>D</b>) in the collapsed conformation () from <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0059683#pone-0059683-g001" target="_blank">Figure 1(B)</a>. The graphs are averaged over sequential groups of 5 residues. (<b>E</b>) Barcode representing the extent of burial (white) and exposure (blue) of all Trigger factor residues upon collapse. (<b>F</b>) These plots are overlaid on the probability graph of formation of contact pairs in NtA2 and HA1 collapses, as in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0059683#pone-0059683-g003" target="_blank">figure 3(D)</a>.