<p>Identification of increased copies of signals of the BAC clone RP11-165H19 mapped to 9p13.3 amplicon in cell line CWR22 and CWR22-Rv1 (A and B). C Optimal signal and lack of cross hybridization was verified using normal metaphase spreads showing two signals for each probe. BAC clone RP11-165H19 signals are green; red signals indicate chromosome 9 centromere (D9Z1).</p
<p>Representative sections of log<sub>2</sub> ratio profiles for undifferentiated (0 d) NHNP cells a...
A–D: Inverted images of DAPI staining. A1–D1: Merged images. Red signals are from the C-genome-speci...
<p><b>A.</b> Normal control metaphase spreads were used to validate the <i>SYK</i> probe (chromosome...
<p>a and b, nine positive super-pools (white arrows) based PCR-screening of 96 super-pools; c, three...
<p>For each FISH analysis, a BAC or cosmid clone containing the indicated gene was Cy3-labelled (pin...
<p>FISH results using the BAC clones with corresponding genome position on chromosome 5p and 21q, de...
<p>(A) BB322D4 without <i>C<sub>0</sub>t</i>-1 DNA blocking, (B) BB322D4 with <i>C<sub>0</sub>t</i>-...
<p>A) Classical and B) Spectral Karyotyping shows key oncogenomic rearrangements present in U-2946 c...
Red signals are from the C-genome-specific probe; DAPI and merged images are shown for each cell. (A...
<p>A) FISH signals derived from two BAC clones 173C03 (green) and 174A01 (red) on extended genomic f...
<p>(a,b) FISH was performed on metaphase chromosomes obtained from peripheral blood with a labeled B...
<p>(P1) BH565D6, (P2) BB69B10, (Q1) BH368F12, (Q2) BH1261C3, (R1) BH1003G1, (R2) BH986B2, (S1) BH431...
<p>(A) Representative images of FISH analysis using probes specific for BRAF (7q34, red) and centrom...
<p>(A1) BH1304, (A2) BH1162H2, (B1) BH783B4, (B2) BH793B11, (C1) BH799B12, (C2) BH1049A9, (D) BB311A...
<p><b>A.</b> Hybridization signals of replicating cells. SS, singlet-singlet: SD, singlet-doublet; D...
<p>Representative sections of log<sub>2</sub> ratio profiles for undifferentiated (0 d) NHNP cells a...
A–D: Inverted images of DAPI staining. A1–D1: Merged images. Red signals are from the C-genome-speci...
<p><b>A.</b> Normal control metaphase spreads were used to validate the <i>SYK</i> probe (chromosome...
<p>a and b, nine positive super-pools (white arrows) based PCR-screening of 96 super-pools; c, three...
<p>For each FISH analysis, a BAC or cosmid clone containing the indicated gene was Cy3-labelled (pin...
<p>FISH results using the BAC clones with corresponding genome position on chromosome 5p and 21q, de...
<p>(A) BB322D4 without <i>C<sub>0</sub>t</i>-1 DNA blocking, (B) BB322D4 with <i>C<sub>0</sub>t</i>-...
<p>A) Classical and B) Spectral Karyotyping shows key oncogenomic rearrangements present in U-2946 c...
Red signals are from the C-genome-specific probe; DAPI and merged images are shown for each cell. (A...
<p>A) FISH signals derived from two BAC clones 173C03 (green) and 174A01 (red) on extended genomic f...
<p>(a,b) FISH was performed on metaphase chromosomes obtained from peripheral blood with a labeled B...
<p>(P1) BH565D6, (P2) BB69B10, (Q1) BH368F12, (Q2) BH1261C3, (R1) BH1003G1, (R2) BH986B2, (S1) BH431...
<p>(A) Representative images of FISH analysis using probes specific for BRAF (7q34, red) and centrom...
<p>(A1) BH1304, (A2) BH1162H2, (B1) BH783B4, (B2) BH793B11, (C1) BH799B12, (C2) BH1049A9, (D) BB311A...
<p><b>A.</b> Hybridization signals of replicating cells. SS, singlet-singlet: SD, singlet-doublet; D...
<p>Representative sections of log<sub>2</sub> ratio profiles for undifferentiated (0 d) NHNP cells a...
A–D: Inverted images of DAPI staining. A1–D1: Merged images. Red signals are from the C-genome-speci...
<p><b>A.</b> Normal control metaphase spreads were used to validate the <i>SYK</i> probe (chromosome...