Relationship between Number of γ-His2Av Foci and Crossover Frequency

<p>The red line is the trend for the percentage of wild-type chromosome 3R <i>(st–ca)</i> crossing over as a function of percentage of wild-type γ-His2Av foci in different <i>mei-P22</i> mutants (diamonds) and <i>mei-W68^L1,</i> a hypomorphic allele (squares). For comparison, two theoretical trends are plotted. (1) The expected crossover frequency assuming a random distribution of DSBs and a crossover will be generated if at least one DSB was made (green line). This prediction takes into account the frequency of bivalents that had no DSB and therefore could not have had a crossover. (2) If the relationship was linear (blue line). Some of the genotypes specifically mentioned in the text are labeled.