Acylcarnitine Analyses

<div><p>(A) Serum acylcarnitine analysis of MCAD^+/+ (<i>n</i> = 4) and MCAD^−/− mice (<i>n</i> = 4)</p><p>There are significant elevations in acylcarnitine species as indicated in MCAD^−/− mice. Values shown are mean values ± standard deviation (SD). Asterisk indicates <i>p</i> < 0.002 and ‡ indicates <i>p</i> < 0.01.</p><p>(B) There are significant elevations in bile acylcarnitines of the same mice shown in (A) as indicated. Values shown are mean values ± SD. Asterisk indicates <i>p</i> < 0.001.</p><p>(C) Bile acylcarnitine profile of an MCAD^−/− mouse compared to a human patient with MCAD deficiency. Internal standards are indicated by an asterisk.</p>