FAAH deficiency affects disposition of hepatic acyl carnitine and acetyl-CoA.

<p>a. Hepatic acyl carnitine profile in 18 h fasted and 5 h re-fed mice. Data are mean ± SEM, n = 4 for FAAH^−/− vs wild-type mice. Non-repeated measures 2-way ANOVA was done to calculate statistical significance. P<0.001 for both row and columns factors. Bonferroni post-tests showed P<0.001 for FAAH^−/− acetylcarnitine. b. Hepatic acetyl-CoA levels in 18 h fasted and 5 h re-fed mice. Data are mean ± SEM, n = 4, **p<0.01 by Student's t-test for FAAH^−/− vs wild-type mice.