Selective inhibitors of AKT positively combine with AC220 in RPMI+10% FBS against MOLM14-luc+ cells.
- Ellen Weisberg (203474)
- Qingsong Liu (381059)
- Xin Zhang (35492)
- Erik Nelson (203494)
- Martin Sattler (203514)
- Feiyang Liu (381060)
- Maria Nicolais (381061)
- Jianming Zhang (139701)
- Constantine Mitsiades (381062)
- Robert W. Smith (381063)
- Richard Stone (86371)
- Ilene Galinsky (64265)
- Atsushi Nonami (381064)
- James D. Griffin (203544)
- Nathanael Gray (157494)
Publication date
February 2013
DOIAbstract
<p>(A–D) Approximately two-day proliferation studies performed with selective AKT inhibitors in combination with AC220 in RPMI+10% FBS. (E) Calcusyn combination indices. The cut-off for nearly additive effects (C.I.: 1.1) is marked by a dashed line.</p
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