<p>(A–B) Approximately two-day proliferation studies performed with selective AKT inhibitors in combination with PKC412 in the presence of RPMI+10% FBS. (C–D) Approximately two-day proliferation studies performed with selective AKT inhibitors in combination with PKC412 in 80% HS-5 SCM. (E) Treatment of MOLM13-luc+ cells with PKC412 in either RPMI+10% FBS or 80% HS-5 SCM.</p
Tumor cells upregulate many cell signaling pathways, with AKT being one of the key kinases to be act...
The serine-threonine kinase AKT, also known as protein kinase B (PKB), was identified in 1977 as the...
Protein kinase B (PKB, also called Akt) is an important regulator of cell proliferation and survival...
<p>(A–C) Approximately two-day proliferation studies performed with selective AKT inhibitors in comb...
<p>(A–D) Approximately two-day proliferation studies performed with selective AKT inhibitors in comb...
<p>(A) Approximately two-day proliferation study performed with MOLM14-luc+ cells cultured in the pr...
<p>(A) Approximately two-day proliferation study performed with a selective Akt inhibitor in combina...
<p>(A–D) Approximately two-day proliferation studies performed with selective AKT inhibitors in comb...
<p>(a) Western blot results for pan-Akt, p-Akt (S473), p-Akt (T308), and tubulin in lysates from 42M...
AbstractAkt is a serine/threonine kinase that transduces survival signals from survival/growth facto...
Akt is a serine/threonine kinase that transduces survival signals from survival/growth factors. Dere...
<p>(a) Cell proliferation results for 42MBGA cells and <i>PTEN</i> corrected derivatives (#7–17, #7–...
<p>Immunoblots of protein lysates prepared from MOLM14-luc+ cells treated for 2 hours with PKC412 (4...
<div><p>Tumor cells upregulate many cell signaling pathways, with AKT being one of the key kinases t...
Tumor cells upregulate many cell signaling pathways, with AKT being one of the key kinases to be act...
Tumor cells upregulate many cell signaling pathways, with AKT being one of the key kinases to be act...
The serine-threonine kinase AKT, also known as protein kinase B (PKB), was identified in 1977 as the...
Protein kinase B (PKB, also called Akt) is an important regulator of cell proliferation and survival...
<p>(A–C) Approximately two-day proliferation studies performed with selective AKT inhibitors in comb...
<p>(A–D) Approximately two-day proliferation studies performed with selective AKT inhibitors in comb...
<p>(A) Approximately two-day proliferation study performed with MOLM14-luc+ cells cultured in the pr...
<p>(A) Approximately two-day proliferation study performed with a selective Akt inhibitor in combina...
<p>(A–D) Approximately two-day proliferation studies performed with selective AKT inhibitors in comb...
<p>(a) Western blot results for pan-Akt, p-Akt (S473), p-Akt (T308), and tubulin in lysates from 42M...
AbstractAkt is a serine/threonine kinase that transduces survival signals from survival/growth facto...
Akt is a serine/threonine kinase that transduces survival signals from survival/growth factors. Dere...
<p>(a) Cell proliferation results for 42MBGA cells and <i>PTEN</i> corrected derivatives (#7–17, #7–...
<p>Immunoblots of protein lysates prepared from MOLM14-luc+ cells treated for 2 hours with PKC412 (4...
<div><p>Tumor cells upregulate many cell signaling pathways, with AKT being one of the key kinases t...
Tumor cells upregulate many cell signaling pathways, with AKT being one of the key kinases to be act...
Tumor cells upregulate many cell signaling pathways, with AKT being one of the key kinases to be act...
The serine-threonine kinase AKT, also known as protein kinase B (PKB), was identified in 1977 as the...
Protein kinase B (PKB, also called Akt) is an important regulator of cell proliferation and survival...