IPA analyses of transcription regulators.

<p>The interaction between transcription factors (inner circle) and both upregulated and downregulated proteins listed in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0062039#pone-0062039-t001" target="_blank">Table 1</a> (outer circle) is shown. Upregulated and down-regulated expressions are indicated in red and green, respectively, the darker the red color the higher level of protein expression. Numbers indicate the protein IDs shown in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0062039#pone-0062039-t001" target="_blank">Table 1</a>. Arrows denote activation, and T-bars represent inhibition. Solid and dashed arrows represent direct and indirect interactions, respectively. All <i>P</i> values of overlap are <10⁻³. Asterisks * and ** indicate <i>P</i> values of overlap <10⁻⁵ and <10⁻⁶, respectively.