<p>Predicted activation or inhibition of activity for selected Transcriptional Regulators (TR) predicted by IPA based on the gene response. A number of transcriptional regulators identified are associated with the pathways in Table B in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0127327#pone.0127327.s002" target="_blank">S2 File</a>. Some regulators may be associated with more than one pathway or stress response, but appear in this table only once.</p><p>*The same TR is identified for both metals.</p><p>**The same TR is differentially affected between Cd and Cr.</p><p>Activation or inhibition of selected transcriptional regulator activity predicted by IPA.</p
<p>The upstream network was generated by IPA and the networks indicate predicted upstream regulators...
<p>The table shows the Ingenuity analysis for prediction of top 5 activated or inhibited transcripti...
†<p>The predicted activation state is inferred from the bias-corrected z-score.</p>††<p>The bias-cor...
<p>The interaction between transcription factors (inner circle) and both upregulated and downregulat...
<p>The predictions of activation or inhibition of transcription regulators are based on the directio...
<p>Transcription regulators identified in the Ingenuity Pathway Analysis Database (IPA) that were di...
<p>(<b>A</b>) Predicted upstream transcriptional regulators from IPA; stimulations analysed independ...
<p>Most activated or inhibited up-stream transcription regulators (transcription factors and ligand-...
(A) Heatmap visualization (IPA activation z-score) of selected IPA functions regulated over the cour...
<p>(<b>A</b>) Predicted activated cytokines from IPA upstream analysis; stimulations analysed indepe...
<p><sup>1</sup>Transcription Factor</p><p><sup>2</sup>The P-value denotes the significance of overla...
<p>Reported is the cross-talk among the transcription factors (TF) in bovine liver uncovered to be e...
<p>Predicted regulations between 7 early stage transcription factors and 7 known iron homeostasis tr...
<p>Predictive analysis (performed by CONREAL) of transcription factor binding sites affected by pote...
<p>IPA analysis identifies 5 upstream regulators related to differentially expressed genes (DEGs).</...
<p>The upstream network was generated by IPA and the networks indicate predicted upstream regulators...
<p>The table shows the Ingenuity analysis for prediction of top 5 activated or inhibited transcripti...
†<p>The predicted activation state is inferred from the bias-corrected z-score.</p>††<p>The bias-cor...
<p>The interaction between transcription factors (inner circle) and both upregulated and downregulat...
<p>The predictions of activation or inhibition of transcription regulators are based on the directio...
<p>Transcription regulators identified in the Ingenuity Pathway Analysis Database (IPA) that were di...
<p>(<b>A</b>) Predicted upstream transcriptional regulators from IPA; stimulations analysed independ...
<p>Most activated or inhibited up-stream transcription regulators (transcription factors and ligand-...
(A) Heatmap visualization (IPA activation z-score) of selected IPA functions regulated over the cour...
<p>(<b>A</b>) Predicted activated cytokines from IPA upstream analysis; stimulations analysed indepe...
<p><sup>1</sup>Transcription Factor</p><p><sup>2</sup>The P-value denotes the significance of overla...
<p>Reported is the cross-talk among the transcription factors (TF) in bovine liver uncovered to be e...
<p>Predicted regulations between 7 early stage transcription factors and 7 known iron homeostasis tr...
<p>Predictive analysis (performed by CONREAL) of transcription factor binding sites affected by pote...
<p>IPA analysis identifies 5 upstream regulators related to differentially expressed genes (DEGs).</...
<p>The upstream network was generated by IPA and the networks indicate predicted upstream regulators...
<p>The table shows the Ingenuity analysis for prediction of top 5 activated or inhibited transcripti...
†<p>The predicted activation state is inferred from the bias-corrected z-score.</p>††<p>The bias-cor...