Correlation and over-representation analyses of H1 variants and histone marks.

<p>(A–B) Genome-wide correlation scatter plots of H1d <i>vs.</i> H1c (A), and GC% (or histone marks) <i>vs.</i> H1d (left) and H1c (right) (B). The correlation coefficient and the trend line were generated as described in methods. X and Y axes: average signal values (normalized to 100 bp window). Pearson's correlation was used to perform the analysis. P<10⁻¹⁰⁰ for all correlation coefficient. (C) Overrepresented features from the following 5 comparisons of H1 or histone mark highly enriched regions; i) H1d/H1c common <i>vs.</i> H3K9me3 regions; ii) H1d/H1c common <i>vs.</i> H3K4me3 regions; iii) H1d/H1c common <i>vs.</i> H3K27me3 regions; iv) H1d/H1c common <i>vs.</i> H1d/H1c unique regions; v) H1d unique <i>vs.</i> H1c unique regions. Bottom half of each box: repetitive elements. *: no significant overrepresentation. All P values remained significant after multiple testing corrections with the FDR method and the more conservative Bonferroni method.