Probe Trials for Morris water maze.

<p>Following learning trials on days two through four, the platform was removed. Mice were allowed to attempt finding the platform location for 60 sec. A) Number of times each mouse correctly crossed the area where the platform had been. *p<0.05 vs. all other groups for all three panels. B) Total distance travelled during the 60 sec in search of the escape platform. ^#p<0.05 young WT vs. old WT. Because there was a significant difference in the distance travelled per trial, owing to differences in swim speed (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0063951#pone-0063951-g005" target="_blank">figure 5</a>), data were then reevaluated following normalization. C) Number of times in 60 sec that mice correctly swam over the previous platform site normalized to the distance travelled. *p<0.05 vs. all other groups.