Overall and immune-related gene expression profiles in intact colon and epithelium.

<p>Heatmaps generated by unsupervised hierarchical clustering of differentially expressed genes. (A) shows all genes differentially expressed within any of the treatment comparisons, and the expression values are derived from individual mice. The bars above the heatmap indicate whether the data are from microdissected (white bar) or intact (black bar) tissue, while those below the heatmap show the age and genotype of the mice as indicated by the colour key. (B) shows a subset of differentially expressed immune related genes from the <i>Il10^−/−</i> mice at 12 weeks <i>vs.</i> C57BL/6J mice at 12 weeks comparison, showing the gene expression profile of each treatment comparison in both intact colon and colon epithelium. Expression values for each gene are averages from 6 arrays per treatment.