<p>This table shows a summary of the most important parameters of the model. Typical rescaled values used in the numerical solution and their relation to typical values for the “real” system are also given. Additional parameters: stiffness of volume conservation: ; decay rate of outside the cell: ; overall area of the cell: (typically with = –); regularization parameter for actin creation: ; parameter describing the steepness of the detachment transition: ; coefficient for nonlinear saturation of adhesion sites: .</p
<p>(A) Maximum change in primary cell orientation () as a function of the strength of substrate atta...
<p>Typical model and response on 20μm×20μm domain (100 samples, actin filament relative density: 0.1...
The cell biomechanical properties play a key role in the determination of the changes during the ess...
Simulations were performed with a center-based model (CBM). In step 1, the contact forces in CBM wer...
Average lifetime of gaps ratio (divided by control case) in first column and average size in second ...
(A) shows the predicted velocity vs substrate stiffness compared to previous studies, (B) shows the ...
<p>The effect of cell contractility on de-adhesion dynamics was studied for three contractility valu...
<p>(<b>A</b>) Standard linear solid (SLS) model of the protrusion. The model includes a Maxwell arm ...
<p>(a) De-adhesion curves computed by varying stiffness ratio () from to keeping , and fixed (se...
(A) Simulation snapshots of DCM cells within a scaled capsule model, for the cases of cells with a r...
<p>Double-logarithmic plots of cell contact radius versus time. (<b>a</b>) varying cell-substrate a...
<p>(A) (a) Examples of measurements of the F-actin intensity of a DMSO control cell and a cell treat...
<p>In real units, we have , min, P, , × J, × J, pN. Note that the choice of for a total number o...
<p>Cell is modeled as a viscoelastic solid (represented by springs and dashpots), and is physically ...
Number of myosin motors and stall force. Extended data availability. Fig A1. Effect of slip and catc...
<p>(A) Maximum change in primary cell orientation () as a function of the strength of substrate atta...
<p>Typical model and response on 20μm×20μm domain (100 samples, actin filament relative density: 0.1...
The cell biomechanical properties play a key role in the determination of the changes during the ess...
Simulations were performed with a center-based model (CBM). In step 1, the contact forces in CBM wer...
Average lifetime of gaps ratio (divided by control case) in first column and average size in second ...
(A) shows the predicted velocity vs substrate stiffness compared to previous studies, (B) shows the ...
<p>The effect of cell contractility on de-adhesion dynamics was studied for three contractility valu...
<p>(<b>A</b>) Standard linear solid (SLS) model of the protrusion. The model includes a Maxwell arm ...
<p>(a) De-adhesion curves computed by varying stiffness ratio () from to keeping , and fixed (se...
(A) Simulation snapshots of DCM cells within a scaled capsule model, for the cases of cells with a r...
<p>Double-logarithmic plots of cell contact radius versus time. (<b>a</b>) varying cell-substrate a...
<p>(A) (a) Examples of measurements of the F-actin intensity of a DMSO control cell and a cell treat...
<p>In real units, we have , min, P, , × J, × J, pN. Note that the choice of for a total number o...
<p>Cell is modeled as a viscoelastic solid (represented by springs and dashpots), and is physically ...
Number of myosin motors and stall force. Extended data availability. Fig A1. Effect of slip and catc...
<p>(A) Maximum change in primary cell orientation () as a function of the strength of substrate atta...
<p>Typical model and response on 20μm×20μm domain (100 samples, actin filament relative density: 0.1...
The cell biomechanical properties play a key role in the determination of the changes during the ess...