Number of myosin motors and stall force. Extended data availability. Fig A1. Effect of slip and catch bonds in cell adhesion behavior. Fig A2. Effect of reinforcement by talin unfolding in cell adhesion. Fig A3. Timeevolutionoftheslipcase. Fig A4. Timeevolutionofthecatchcase. Fig A5. Number of equispaced ligands nc as a function of the adhesion radius. Fig A6. Comparison of the number of MC simulations for two different final times tf = 100s and tf = 1000s. Fig A7. Mean and standard deviation of the force Fc (pN) computed over bound binders. Fig A8. Sensitivity analysis of the reinforced case. Table A1. Model parameters for slip and catch cases. Table A2. Parameters for myosin motors used inside Eqs. 1, 2 and 3, with experimental references...
(a) From bottom to top, a single adhesion chain made of a substrate (green), represented as a spring...
AbstractThe mechanical stiffness of a cell’s environment exerts a strong, but variable, influence on...
In recent years, research in cell biology has shown that mechanics is a key to cell response, differ...
Cell motility relies on the continuous reorganization of a dynamic actin–myosin–adhesion network at ...
<p>(A) Maximum change in primary cell orientation () as a function of the strength of substrate atta...
University of Minnesota Ph.D. dissertation. Septemberv 2014. Major: Chemical Engineering. Advisor: D...
University of Minnesota Ph.D. dissertation. December 2008. Major: Biomedical Engineering. Advisor: D...
A. A heatmap of the average percentage of ligand bound integrins varying substrate stiffness, k, bet...
Matlab code for a multi-scale clutch model and the full set of figures associated with the article "...
By considering the molecular and mechanical properties of actin filaments, myosin motors, adaptor pr...
International audienceWhen crawling on a flat substrate, living cells exert forces on it via adhesiv...
Cells interact with the extracellular matrix (ECM) via cell–ECM adhesions. These physical interactio...
none3siWe apply a recently developed model of cytoskeletal force generation to study a cell’s intrin...
A. Average percentage of ligated integrins varying the width of the actin fiber and using Pbundling ...
The remodeling of the cytoskeleton and focal adhesion distributions for cells on substrates with mic...
(a) From bottom to top, a single adhesion chain made of a substrate (green), represented as a spring...
AbstractThe mechanical stiffness of a cell’s environment exerts a strong, but variable, influence on...
In recent years, research in cell biology has shown that mechanics is a key to cell response, differ...
Cell motility relies on the continuous reorganization of a dynamic actin–myosin–adhesion network at ...
<p>(A) Maximum change in primary cell orientation () as a function of the strength of substrate atta...
University of Minnesota Ph.D. dissertation. Septemberv 2014. Major: Chemical Engineering. Advisor: D...
University of Minnesota Ph.D. dissertation. December 2008. Major: Biomedical Engineering. Advisor: D...
A. A heatmap of the average percentage of ligand bound integrins varying substrate stiffness, k, bet...
Matlab code for a multi-scale clutch model and the full set of figures associated with the article "...
By considering the molecular and mechanical properties of actin filaments, myosin motors, adaptor pr...
International audienceWhen crawling on a flat substrate, living cells exert forces on it via adhesiv...
Cells interact with the extracellular matrix (ECM) via cell–ECM adhesions. These physical interactio...
none3siWe apply a recently developed model of cytoskeletal force generation to study a cell’s intrin...
A. Average percentage of ligated integrins varying the width of the actin fiber and using Pbundling ...
The remodeling of the cytoskeleton and focal adhesion distributions for cells on substrates with mic...
(a) From bottom to top, a single adhesion chain made of a substrate (green), represented as a spring...
AbstractThe mechanical stiffness of a cell’s environment exerts a strong, but variable, influence on...
In recent years, research in cell biology has shown that mechanics is a key to cell response, differ...