Effects of MS and Kindling on EEG spectral activity.

<p>EEG spectral activities were analysed from rats under neuroleptic analgesia (A1–C1) as well as freely moving rats (A2–C2). Total power in the low frequency delta 1–4 Hz band was significantly increased in kindled rats, compared to sham-kindled rats when measured in rats under neuroleptic analgesia (F_(3,34) = 11.9, p = 0.04, panel B1) and in freely moving rats (F_(3,47) = 15.4, p = 0.004, panel B2). Also, in freely moving rats, MS led to a significant decrease in the power of delta frequency activity (F_(3,47) = 7.26, p = 0.04, panel B2). In the 5–9 Hz frequency band, there were no significant effect of MS or kindling observed in rats under neuroleptic analgesia (C1), but in freely moving rats, there was a significant increase in power of 5–9 Hz frequency in kindled rats, compared to sham-kindled rats (C2). There was no significant effect of kindling or MS on power of higher frequencies (p>0.05; data not shown). Data are expressed as Mean ± SEM.