<p>(A) Box and whisker plots for “Deletion Size,” which measures the median size of deletions within a 2-Mb window centered on the gene, common fragile site genes (orange) and tumor suppressor genes (blue) (B) Box and whisker plots for “Deletion Separation,” which measures the separation (non-overlapping) of deletions within a 2-Mb window centered on the gene, (C) The co-deletion tendency of common fragile site genes (orange) and tumor suppressor genes (blue) relative to the co-deletion of genes of different classes (gray).</p
<p>(A) Deletions detected by CGH arrays. Each arc represents the deleted region in an isolate with t...
Homozygous deletions are rare in cancers and often target tumour suppressor genes. Here, we build a ...
<p>(A) Genetic map of <i>xehypBA1</i>, <i>xehypBA2</i>, and <i>xehypAA</i> of <i>X</i>. <i>euvesicat...
<p>Scatter dot plots of values for statistics that distinguish focal deletions affecting common frag...
<p>Genes that had 15 or more focal deletions (4,823) were analyzed by the unsupervised learning meth...
<p>(A) The frequency with which the indicated common fragile site or CFS-like gene is deleted in dif...
One of the key questions about genomic alterations in cancer is whether they are functional in the s...
One of the key questions about genomic alterations in cancer is whether they are functional in the s...
<p>For deletions A, 1, 5, 7 and 12, both breakpoint regions joined by the deletion are shown. These ...
One of the key questions about genomic alterations in cancer is whether they are functional in the s...
<p>Each of the four panels shows (top) an ideogram of the chromosome on which the featured gene is l...
<p>All <i>FOXL2</i> encompassing deletions were initially identified using MLPA. The regulatory dele...
<p>(A) A schematic of the experiment, which used a custom tiling array to determine if aphidicolin i...
The landscape of somatic acquired deletions in cancer cells is shaped by positive and negative selec...
SummaryCancer genomes exhibit numerous deletions, some of which inactivate tumor suppressor genes an...
<p>(A) Deletions detected by CGH arrays. Each arc represents the deleted region in an isolate with t...
Homozygous deletions are rare in cancers and often target tumour suppressor genes. Here, we build a ...
<p>(A) Genetic map of <i>xehypBA1</i>, <i>xehypBA2</i>, and <i>xehypAA</i> of <i>X</i>. <i>euvesicat...
<p>Scatter dot plots of values for statistics that distinguish focal deletions affecting common frag...
<p>Genes that had 15 or more focal deletions (4,823) were analyzed by the unsupervised learning meth...
<p>(A) The frequency with which the indicated common fragile site or CFS-like gene is deleted in dif...
One of the key questions about genomic alterations in cancer is whether they are functional in the s...
One of the key questions about genomic alterations in cancer is whether they are functional in the s...
<p>For deletions A, 1, 5, 7 and 12, both breakpoint regions joined by the deletion are shown. These ...
One of the key questions about genomic alterations in cancer is whether they are functional in the s...
<p>Each of the four panels shows (top) an ideogram of the chromosome on which the featured gene is l...
<p>All <i>FOXL2</i> encompassing deletions were initially identified using MLPA. The regulatory dele...
<p>(A) A schematic of the experiment, which used a custom tiling array to determine if aphidicolin i...
The landscape of somatic acquired deletions in cancer cells is shaped by positive and negative selec...
SummaryCancer genomes exhibit numerous deletions, some of which inactivate tumor suppressor genes an...
<p>(A) Deletions detected by CGH arrays. Each arc represents the deleted region in an isolate with t...
Homozygous deletions are rare in cancers and often target tumour suppressor genes. Here, we build a ...
<p>(A) Genetic map of <i>xehypBA1</i>, <i>xehypBA2</i>, and <i>xehypAA</i> of <i>X</i>. <i>euvesicat...