<p><b>A)</b><b> </b> BDNF protein levels in the temporal cortex of wild-type mice and mice carrying <i>APdE9</i> and/or <i>Bdnf</i><sup>+/−</sup> mutations. <b>B)</b> BDNF protein levels in the hippocampus of wild-type mice and mice carrying <i>APdE9</i> and/or <i>Bdnf</i><sup>+/−</sup> mutations. Two-Way ANOVA followed with Tukey-Kramer <i>post hoc</i> test was performed for statistical analysis. *p<0.05, ***p<0.001 compared to the respective wt, ###p<0.001 compared to wt/wt.</p
<p>All four genotypes are pooled, with n = 29-31 in all correlations. Values are Spearman rho correl...
<p>(<b>A</b>) Quantification of the intensity of pCREB immunoreactivity associated with NeuN-labeled...
Brain-derived neurotrophic factor (BDNF) is a candidate molecule for regulating activity-dependent s...
<p>Western blot analysis of mature-BDNF protein levels in the cortex of wild-type mice and mice carr...
<p><b>A)</b> BDNF protein levels (measured with ELISA) in the hippocampus, frontal cortex, parietal ...
<p><b>A)</b> Example of an amyloid plaque (green) in the hippocampus surrounded by phosho-tau positi...
Brain-derived neurotrophic factor (BDNF) importantly regulates learning and memory and supports the ...
<p>(<b>A</b>) Swim path length to the hidden platform in males; <b>** s</b>ignificant <i>APdE9</i> g...
<p><b>A.</b> RT-PCR measures of the 4 BDNF transcripts show a decrease in BDNF transcripts 1, 2 and ...
<p>(A) Transcript levels of <i>Bdnf</i> exon IV in CA1 and CA3 regions of hippocampus in P10 <i>Jaco...
<p>Transmitted light microscope images showing representative Nissl-stained coronal sections of a wi...
<p>Representative confocal laser scanning microscopy images of dual-label immunofluorescence for CAL...
<p>(<b>A–B</b>) Western blot analysis on whole brain homogenates from homozygous 3xTg-AD mice reveal...
Genetic deletion of a single allele of the BDNF gene affects hippocampal LTP and causes several beha...
<p>Copy numbers of mature BDNF transcript were normalized by dividing the copy number of the referen...
<p>All four genotypes are pooled, with n = 29-31 in all correlations. Values are Spearman rho correl...
<p>(<b>A</b>) Quantification of the intensity of pCREB immunoreactivity associated with NeuN-labeled...
Brain-derived neurotrophic factor (BDNF) is a candidate molecule for regulating activity-dependent s...
<p>Western blot analysis of mature-BDNF protein levels in the cortex of wild-type mice and mice carr...
<p><b>A)</b> BDNF protein levels (measured with ELISA) in the hippocampus, frontal cortex, parietal ...
<p><b>A)</b> Example of an amyloid plaque (green) in the hippocampus surrounded by phosho-tau positi...
Brain-derived neurotrophic factor (BDNF) importantly regulates learning and memory and supports the ...
<p>(<b>A</b>) Swim path length to the hidden platform in males; <b>** s</b>ignificant <i>APdE9</i> g...
<p><b>A.</b> RT-PCR measures of the 4 BDNF transcripts show a decrease in BDNF transcripts 1, 2 and ...
<p>(A) Transcript levels of <i>Bdnf</i> exon IV in CA1 and CA3 regions of hippocampus in P10 <i>Jaco...
<p>Transmitted light microscope images showing representative Nissl-stained coronal sections of a wi...
<p>Representative confocal laser scanning microscopy images of dual-label immunofluorescence for CAL...
<p>(<b>A–B</b>) Western blot analysis on whole brain homogenates from homozygous 3xTg-AD mice reveal...
Genetic deletion of a single allele of the BDNF gene affects hippocampal LTP and causes several beha...
<p>Copy numbers of mature BDNF transcript were normalized by dividing the copy number of the referen...
<p>All four genotypes are pooled, with n = 29-31 in all correlations. Values are Spearman rho correl...
<p>(<b>A</b>) Quantification of the intensity of pCREB immunoreactivity associated with NeuN-labeled...
Brain-derived neurotrophic factor (BDNF) is a candidate molecule for regulating activity-dependent s...