<p>wG-BLUP uses all SNPs (p = 400 K), but the contribution of each SNP to the genomic relationship matrix was weighted using as weight, where is the SNP associated p-value reported by the GIANT consortium <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1003608#pgen.1003608-LangoAllen1" target="_blank">[5]</a>.</p
Non-additive genetic variation is usually ignored when genome-wide markers are used to study the gen...
We have recently developed analysis methods (GREML) to estimate the genetic variance of a complex tr...
<p>(To increase readability, the log<sub>10</sub>(BFs) are truncated at 20). (A) Genome-wide log<sub...
<p>Relationship between GREML-based heritability estimates (Genetic Variance/Phenotypic Variance) an...
<p><sup>a</sup>Posterior mean, posterior standard deviation and 95% Highest Probability Density Inte...
<p>N-FHS = Number of records from Framingham, N-GEN = Number of records from GENEVA. G-BLUP uses 400...
a<p>Estimate of variance explained by all SNPs with its standard error given in the parentheses. A f...
<p>The proportion of GWAS significant SNPs (<i>θ</i><sub>P</sub>) is defined as the proportion of SN...
<p>The trait analyzed is first-visit SBP and DBP and long-term average (LTA) SBP and DBP respectivel...
Best linear unbiased prediction (BLUP) has been used to estimate the fixed effects and random effect...
<p> indicates the number of SNP markers used in the model being evaluated. All other values indicate...
<p>The first three columns are the averaged standard error observed from 100 simulations under three...
We established a genomic model of quantitative trait with genomic additive and dominance relationshi...
<div><p>We established a genomic model of quantitative trait with genomic additive and dominance rel...
1<p>h<sup>2</sup>(g), heritability of additive genetic variance; h<sup>2</sup> (gxe), heritability o...
Non-additive genetic variation is usually ignored when genome-wide markers are used to study the gen...
We have recently developed analysis methods (GREML) to estimate the genetic variance of a complex tr...
<p>(To increase readability, the log<sub>10</sub>(BFs) are truncated at 20). (A) Genome-wide log<sub...
<p>Relationship between GREML-based heritability estimates (Genetic Variance/Phenotypic Variance) an...
<p><sup>a</sup>Posterior mean, posterior standard deviation and 95% Highest Probability Density Inte...
<p>N-FHS = Number of records from Framingham, N-GEN = Number of records from GENEVA. G-BLUP uses 400...
a<p>Estimate of variance explained by all SNPs with its standard error given in the parentheses. A f...
<p>The proportion of GWAS significant SNPs (<i>θ</i><sub>P</sub>) is defined as the proportion of SN...
<p>The trait analyzed is first-visit SBP and DBP and long-term average (LTA) SBP and DBP respectivel...
Best linear unbiased prediction (BLUP) has been used to estimate the fixed effects and random effect...
<p> indicates the number of SNP markers used in the model being evaluated. All other values indicate...
<p>The first three columns are the averaged standard error observed from 100 simulations under three...
We established a genomic model of quantitative trait with genomic additive and dominance relationshi...
<div><p>We established a genomic model of quantitative trait with genomic additive and dominance rel...
1<p>h<sup>2</sup>(g), heritability of additive genetic variance; h<sup>2</sup> (gxe), heritability o...
Non-additive genetic variation is usually ignored when genome-wide markers are used to study the gen...
We have recently developed analysis methods (GREML) to estimate the genetic variance of a complex tr...
<p>(To increase readability, the log<sub>10</sub>(BFs) are truncated at 20). (A) Genome-wide log<sub...