Frequency of over expression of MCM genes with advancing stage of disease.

Amplification and over-expression of the MDM2 gene in human soft tissue tumours

Patterson, Helen
Barnes, Diana
Gill, Sandra
Spicer, James
Fisher, Cyril
Thomas, Merion
Grimer, Robert
Fletcher, Chris
Gusterson, Barry
Cooper, Colin

January 1997

Purpose. Amplification of genetic sequences on chromosome 12q13 is frequently found in soft tissue t...

Mean DNA methylation levels for hypermethylated genes sorted by group.

Árpád V. Patai (132272)
Gábor Valcz (466332)
Péter Hollósi (155769)
Alexandra Kalmár (123738)
Bálint Péterfia (130981)
Árpád Patai (785267)
Barnabás Wichmann (123721)
Sándor Spisák (123726)
Barbara Kinga Barták (785268)
Katalin Leiszter (123735)
Kinga Tóth (123732)
Ferenc Sipos (123723)
Ilona Kovalszky (130989)
Zoltán Péter (785269)
Pál Miheller (677099)
Zsolt Tulassay (123741)
Béla Molnár (123745)

August 2015

A. Genes commonly methylated in >95% of all samples.B. Genes methylated in a...

Top 11 genes most frequently overexpressed through amplification in 17p11.2-p12.

Joeri Both (186274)
Thijs Wu (186277)
Johannes Bras (186280)
Gerard R. Schaap (186283)
Frank Baas (23060)
Theo J. M. Hulsebos (186286)

January 2012

Genes were scored for the number of times a feature was found in the tumour (data taken from Supp...

Expression of MCM genes in different tumor stages.

Mitali Das (200861)
Shyam Babu Prasad (434235)
Suresh Singh Yadav (434236)
H. B. Govardhan (434237)
Lakshmi Kant Pandey (434238)
Sunita Singh (73953)
Satyajit Pradhan (434239)
Gopeshwar Narayan (2799)

July 2013

Normalized expression level of (A) MCM2, (B) MCM4, (C) MCM5, (D) MCM6, (E) MCM10 and (F) RECQL4 i...

Percentage of mCRC patients with MSI tumors and loss of MLH1 and/or PMS2 (MLH1 / PMS2) and MSH2 and/or MSH6, (MSH2 and MSH6) subdivided in patients with MSI / EMAST tumors and patients with MSI / non-EMAST tumors.

Sabine Venderbosch (725696)
Shannon van Lent—van Vliet (725697)
Anton F. J. de Haan (725698)
Marjolijn J. Ligtenberg (154122)
Monique Goossens (725699)
Cornelis J. A. Punt (427413)
Miriam Koopman (437119)
Iris D. Nagtegaal (359517)

April 2015

(A). Percentage of patients with known Lynch syndrome and germ line mutation of the different MSI...

Methylation status and frequency of top 10 hypermethylated genes in tumor samples.

Árpád V. Patai (132272)
Gábor Valcz (466332)
Péter Hollósi (155769)
Alexandra Kalmár (123738)
Bálint Péterfia (130981)
Árpád Patai (785267)
Barnabás Wichmann (123721)
Sándor Spisák (123726)
Barbara Kinga Barták (785268)
Katalin Leiszter (123735)
Kinga Tóth (123732)
Ferenc Sipos (123723)
Ilona Kovalszky (130989)
Zoltán Péter (785269)
Pál Miheller (677099)
Zsolt Tulassay (123741)
Béla Molnár (123745)

August 2015

List of the top 10 genes that were hypermethylated in at least 85% of benign and malignant tumor ...

Expression levels of 19 genes that display >two-fold differences in expression between metastasising and non-metastasising MCTs.

Kelly Bowlt Blacklock (6102878)
Zeynep Birand (6102881)
Deborah Biasoli (445467)
Elena Fineberg (395222)
Sue Murphy (2205058)
Debs Flack (6102884)
Joyce Bass (2205037)
Stefano Di Palma (6102887)
Laura Blackwood (6102890)
Jenny McKay (3080568)
Trevor Whitbread (6102893)
Richard Fox (153532)
Tom Eve (6102896)
Stuart Beaver (6102899)
Mike Starkey (2205052)

December 2018

The bottom and top of each box denote the expression measurements that encompass the values shared b...

Frequency of instable EMAST markers (A) and frequency of affected EMAST loci (B), subdivided by patients with MSI and MSS tumors.

Sabine Venderbosch (725696)
Shannon van Lent—van Vliet (725697)
Anton F. J. de Haan (725698)
Marjolijn J. Ligtenberg (154122)
Monique Goossens (725699)
Cornelis J. A. Punt (427413)
Miriam Koopman (437119)
Iris D. Nagtegaal (359517)

April 2015

Frequency of instable EMAST markers (A) and frequency of affected EMAST loci (B), subdivided by p...

MCM4 expression.

Mitali Das (200861)
Shyam Babu Prasad (434235)
Suresh Singh Yadav (434236)
H. B. Govardhan (434237)
Lakshmi Kant Pandey (434238)
Sunita Singh (73953)
Satyajit Pradhan (434239)
Gopeshwar Narayan (2799)

July 2013

(A) Electrophoregram of semi-quantitative RT-PCR showing MCM4 expression in cell lines, primary t...

Distribution of expression of MCMs in different types of lesion of cervical cancer.

Mitali Das (200861)
Shyam Babu Prasad (434235)
Suresh Singh Yadav (434236)
H. B. Govardhan (434237)
Lakshmi Kant Pandey (434238)
Sunita Singh (73953)
Satyajit Pradhan (434239)
Gopeshwar Narayan (2799)

July 2013

Differential expression of (A) MCM4; (B) MCM5; (C) MCM6 in different types of lesions viz. infilt...

Gene methylation status and tumor subtypes.

Songping Wang (160963)
Tiffany H. Dorsey (160966)
Atsushi Terunuma (160968)
Rick A. Kittles (160971)
Stefan Ambs (37080)
Bernard Kwabi-Addo (45546)

May 2012

Percentage methylation frequency stratified by subtype: A. Triple-negative (TN) tumors (n ...

Genes exhibiting differential expression between metastasising and non-metastasising MCTs.

Kelly Bowlt Blacklock (6102878)
Zeynep Birand (6102881)
Deborah Biasoli (445467)
Elena Fineberg (395222)
Sue Murphy (2205058)
Debs Flack (6102884)
Joyce Bass (2205037)
Stefano Di Palma (6102887)
Laura Blackwood (6102890)
Jenny McKay (3080568)
Trevor Whitbread (6102893)
Richard Fox (153532)
Tom Eve (6102896)
Stuart Beaver (6102899)
Mike Starkey (2205052)

December 2018

Expression of 218 genes in 18 metastasising (M) and 16 non-metastasising (NM) MCTs. Each sphere repr...

MDAD plots of cancer-associated HK genes.

Meili Chen (278448)
Jingfa Xiao (134638)
Zhang Zhang (14172)
Jingxing Liu (278450)
Jiayan Wu (204411)
Jun Yu (5904)

January 2013

MD<0 means the gene expression span width in cancer condition is larger than that in norma...

A. Total number of shortlisted putative disease genes with abnormal behavior (either up-regulated and/or network rewired) in each stage during melanoma progression. B. Number of shortlisted genes conserved across multiple stages which is comparatively many fold higher than DE genes alone. C. Number of different known tumor associated genes (tumor suppressor, oncogene and other tumor associated genes) identified among shortlisted disease genes for each stage. D. Oncogenes identified in each melanoma stage, the genes common in each stage are also displayed as intersections. E. Line graph showing the frequency of differential correlation coefficient observed for each edge between putative disease genes in each melanoma stage network versus control network. High value of differential correlation coefficient means high strength of association between disease genes in perturbed network as compared to normal.

Abhinav Kaushik (814425)
Yashuma Bhatia (825217)
Shakir Ali (825218)
Dinesh Gupta (19194)

November 2015

A. Total number of shortlisted putative disease genes with abnormal behavior (either up-regulated...

Average number of methylated genes per tumor type.

Megan L. Durr (364557)
Wojciech K. Mydlarz (364558)
Chunbo Shao (49901)
Marianna L. Zahurak (364559)
Alice Y. Chuang (364561)
Mohammad O. Hoque (364562)
William H. Westra (121394)
Nanette J. Liegeois (364565)
Joseph A. Califano (121399)
David Sidransky (11085)
Patrick K. Ha (119730)

February 2013

†Calculated as any level of methylation detected within the 19 genes tested.*significantly...

Amplification and over-expression of the MDM2 gene in human soft tissue tumours

Patterson, Helen
Barnes, Diana
Gill, Sandra
Spicer, James
Fisher, Cyril
Thomas, Merion
Grimer, Robert
Fletcher, Chris
Gusterson, Barry
Cooper, Colin

January 1997

Purpose. Amplification of genetic sequences on chromosome 12q13 is frequently found in soft tissue t...

Mean DNA methylation levels for hypermethylated genes sorted by group.

Árpád V. Patai (132272)
Gábor Valcz (466332)
Péter Hollósi (155769)
Alexandra Kalmár (123738)
Bálint Péterfia (130981)
Árpád Patai (785267)
Barnabás Wichmann (123721)
Sándor Spisák (123726)
Barbara Kinga Barták (785268)
Katalin Leiszter (123735)
Kinga Tóth (123732)
Ferenc Sipos (123723)
Ilona Kovalszky (130989)
Zoltán Péter (785269)
Pál Miheller (677099)
Zsolt Tulassay (123741)
Béla Molnár (123745)

August 2015

A. Genes commonly methylated in >95% of all samples.B. Genes methylated in a...

Top 11 genes most frequently overexpressed through amplification in 17p11.2-p12.

Joeri Both (186274)
Thijs Wu (186277)
Johannes Bras (186280)
Gerard R. Schaap (186283)
Frank Baas (23060)
Theo J. M. Hulsebos (186286)

January 2012

Genes were scored for the number of times a feature was found in the tumour (data taken from Supp...

Expression of MCM genes in different tumor stages.

Mitali Das (200861)
Shyam Babu Prasad (434235)
Suresh Singh Yadav (434236)
H. B. Govardhan (434237)
Lakshmi Kant Pandey (434238)
Sunita Singh (73953)
Satyajit Pradhan (434239)
Gopeshwar Narayan (2799)

July 2013

Normalized expression level of (A) MCM2, (B) MCM4, (C) MCM5, (D) MCM6, (E) MCM10 and (F) RECQL4 i...

Percentage of mCRC patients with MSI tumors and loss of MLH1 and/or PMS2 (MLH1 / PMS2) and MSH2 and/or MSH6, (MSH2 and MSH6) subdivided in patients with MSI / EMAST tumors and patients with MSI / non-EMAST tumors.

Sabine Venderbosch (725696)
Shannon van Lent—van Vliet (725697)
Anton F. J. de Haan (725698)
Marjolijn J. Ligtenberg (154122)
Monique Goossens (725699)
Cornelis J. A. Punt (427413)
Miriam Koopman (437119)
Iris D. Nagtegaal (359517)

April 2015

(A). Percentage of patients with known Lynch syndrome and germ line mutation of the different MSI...

Methylation status and frequency of top 10 hypermethylated genes in tumor samples.

Árpád V. Patai (132272)
Gábor Valcz (466332)
Péter Hollósi (155769)
Alexandra Kalmár (123738)
Bálint Péterfia (130981)
Árpád Patai (785267)
Barnabás Wichmann (123721)
Sándor Spisák (123726)
Barbara Kinga Barták (785268)
Katalin Leiszter (123735)
Kinga Tóth (123732)
Ferenc Sipos (123723)
Ilona Kovalszky (130989)
Zoltán Péter (785269)
Pál Miheller (677099)
Zsolt Tulassay (123741)
Béla Molnár (123745)

August 2015

List of the top 10 genes that were hypermethylated in at least 85% of benign and malignant tumor ...

Expression levels of 19 genes that display >two-fold differences in expression between metastasising and non-metastasising MCTs.

Kelly Bowlt Blacklock (6102878)
Zeynep Birand (6102881)
Deborah Biasoli (445467)
Elena Fineberg (395222)
Sue Murphy (2205058)
Debs Flack (6102884)
Joyce Bass (2205037)
Stefano Di Palma (6102887)
Laura Blackwood (6102890)
Jenny McKay (3080568)
Trevor Whitbread (6102893)
Richard Fox (153532)
Tom Eve (6102896)
Stuart Beaver (6102899)
Mike Starkey (2205052)

December 2018

The bottom and top of each box denote the expression measurements that encompass the values shared b...

Frequency of instable EMAST markers (A) and frequency of affected EMAST loci (B), subdivided by patients with MSI and MSS tumors.

Sabine Venderbosch (725696)
Shannon van Lent—van Vliet (725697)
Anton F. J. de Haan (725698)
Marjolijn J. Ligtenberg (154122)
Monique Goossens (725699)
Cornelis J. A. Punt (427413)
Miriam Koopman (437119)
Iris D. Nagtegaal (359517)

April 2015

Frequency of instable EMAST markers (A) and frequency of affected EMAST loci (B), subdivided by p...

MCM4 expression.

Mitali Das (200861)
Shyam Babu Prasad (434235)
Suresh Singh Yadav (434236)
H. B. Govardhan (434237)
Lakshmi Kant Pandey (434238)
Sunita Singh (73953)
Satyajit Pradhan (434239)
Gopeshwar Narayan (2799)

July 2013

(A) Electrophoregram of semi-quantitative RT-PCR showing MCM4 expression in cell lines, primary t...

Distribution of expression of MCMs in different types of lesion of cervical cancer.

Mitali Das (200861)
Shyam Babu Prasad (434235)
Suresh Singh Yadav (434236)
H. B. Govardhan (434237)
Lakshmi Kant Pandey (434238)
Sunita Singh (73953)
Satyajit Pradhan (434239)
Gopeshwar Narayan (2799)

July 2013

Differential expression of (A) MCM4; (B) MCM5; (C) MCM6 in different types of lesions viz. infilt...

Gene methylation status and tumor subtypes.

Songping Wang (160963)
Tiffany H. Dorsey (160966)
Atsushi Terunuma (160968)
Rick A. Kittles (160971)
Stefan Ambs (37080)
Bernard Kwabi-Addo (45546)

May 2012

Percentage methylation frequency stratified by subtype: A. Triple-negative (TN) tumors (n ...

Genes exhibiting differential expression between metastasising and non-metastasising MCTs.

Kelly Bowlt Blacklock (6102878)
Zeynep Birand (6102881)
Deborah Biasoli (445467)
Elena Fineberg (395222)
Sue Murphy (2205058)
Debs Flack (6102884)
Joyce Bass (2205037)
Stefano Di Palma (6102887)
Laura Blackwood (6102890)
Jenny McKay (3080568)
Trevor Whitbread (6102893)
Richard Fox (153532)
Tom Eve (6102896)
Stuart Beaver (6102899)
Mike Starkey (2205052)

December 2018

Expression of 218 genes in 18 metastasising (M) and 16 non-metastasising (NM) MCTs. Each sphere repr...

MDAD plots of cancer-associated HK genes.

Meili Chen (278448)
Jingfa Xiao (134638)
Zhang Zhang (14172)
Jingxing Liu (278450)
Jiayan Wu (204411)
Jun Yu (5904)

January 2013

MD<0 means the gene expression span width in cancer condition is larger than that in norma...

A. Total number of shortlisted putative disease genes with abnormal behavior (either up-regulated and/or network rewired) in each stage during melanoma progression. B. Number of shortlisted genes conserved across multiple stages which is comparatively many fold higher than DE genes alone. C. Number of different known tumor associated genes (tumor suppressor, oncogene and other tumor associated genes) identified among shortlisted disease genes for each stage. D. Oncogenes identified in each melanoma stage, the genes common in each stage are also displayed as intersections. E. Line graph showing the frequency of differential correlation coefficient observed for each edge between putative disease genes in each melanoma stage network versus control network. High value of differential correlation coefficient means high strength of association between disease genes in perturbed network as compared to normal.

Abhinav Kaushik (814425)
Yashuma Bhatia (825217)
Shakir Ali (825218)
Dinesh Gupta (19194)

November 2015

A. Total number of shortlisted putative disease genes with abnormal behavior (either up-regulated...

Average number of methylated genes per tumor type.

Megan L. Durr (364557)
Wojciech K. Mydlarz (364558)
Chunbo Shao (49901)
Marianna L. Zahurak (364559)
Alice Y. Chuang (364561)
Mohammad O. Hoque (364562)
William H. Westra (121394)
Nanette J. Liegeois (364565)
Joseph A. Califano (121399)
David Sidransky (11085)
Patrick K. Ha (119730)

February 2013

†Calculated as any level of methylation detected within the 19 genes tested.*significantly...

Amplification and over-expression of the MDM2 gene in human soft tissue tumours

Patterson, Helen
Barnes, Diana
Gill, Sandra
Spicer, James
Fisher, Cyril
Thomas, Merion
Grimer, Robert
Fletcher, Chris
Gusterson, Barry
Cooper, Colin

January 1997

Purpose. Amplification of genetic sequences on chromosome 12q13 is frequently found in soft tissue t...

Mean DNA methylation levels for hypermethylated genes sorted by group.

Árpád V. Patai (132272)
Gábor Valcz (466332)
Péter Hollósi (155769)
Alexandra Kalmár (123738)
Bálint Péterfia (130981)
Árpád Patai (785267)
Barnabás Wichmann (123721)
Sándor Spisák (123726)
Barbara Kinga Barták (785268)
Katalin Leiszter (123735)
Kinga Tóth (123732)
Ferenc Sipos (123723)
Ilona Kovalszky (130989)
Zoltán Péter (785269)
Pál Miheller (677099)
Zsolt Tulassay (123741)
Béla Molnár (123745)

August 2015

A. Genes commonly methylated in >95% of all samples.B. Genes methylated in a...

Top 11 genes most frequently overexpressed through amplification in 17p11.2-p12.

Joeri Both (186274)
Thijs Wu (186277)
Johannes Bras (186280)
Gerard R. Schaap (186283)
Frank Baas (23060)
Theo J. M. Hulsebos (186286)

January 2012

Genes were scored for the number of times a feature was found in the tumour (data taken from Supp...

Frequency of over expression of MCM genes with advancing stage of disease.

Abstract

Extracted data

Frequency of over expression of MCM genes with advancing stage of disease.

Abstract

Extracted data

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