<p>Genes were scored for the number of times a feature was found in the tumour (data taken from Supplemental <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0030907#pone.0030907.s001" target="_blank">Figure S1</a>). A: number of tumours with amplification of a gene; O: number of tumours with overexpression of that gene; O/A: number of tumours with overexpression and amplification of that gene; %: percentage of tumours in which the amplified gene is overexpressed.</p
Gene amplification was recognized as a physiological process during the development of Drosophila me...
Imbalanced expression of somatic alleles in cancer can suggest functional and selective features, an...
Dominant functional categories (rows) enriched in the large list of 5602 genes (columns) having incr...
<p>List of the top 20 amplified genes ordered by decreasing sum of score values. Nm: number of modul...
<p>Boxes contain expression values between the 25<sup>th</sup> and 75<sup>th</sup> percentile in the...
<p>(<b>A</b>) Enrichment analysis of the top 100 genes with the highest gene average gravitation sco...
<p>For each human gene, the expected number of mutations is obtained based on the normal mutation pa...
© 2013 Dr. Sally Jayne DavisGenomic copy number amplification is a hallmark of oncogene-associated t...
<p>Genes that are known to be associated with cancer (black) and all remaining genes (gray) were gro...
Ovarian cancer is a disease characterised by complex genomic rearrangements but the majority of the ...
Ovarian cancer is a disease characterised by complex genomic rearrangements but the majority of the ...
Amplification of 8p11-12 is a well-known alteration in human breast cancers but the driving oncogene...
<p>Top 10 genes that showed the highest amount of overexpression in FTO-4 mice per tissue.</p
Chromosome region 17q12-23 commonly shows an increase in DNA copy number in breast cancers, suggesti...
<p>Percentages are the proportion of tumors having a mutation within a subtype, e.g. 37% of Bronchio...
Gene amplification was recognized as a physiological process during the development of Drosophila me...
Imbalanced expression of somatic alleles in cancer can suggest functional and selective features, an...
Dominant functional categories (rows) enriched in the large list of 5602 genes (columns) having incr...
<p>List of the top 20 amplified genes ordered by decreasing sum of score values. Nm: number of modul...
<p>Boxes contain expression values between the 25<sup>th</sup> and 75<sup>th</sup> percentile in the...
<p>(<b>A</b>) Enrichment analysis of the top 100 genes with the highest gene average gravitation sco...
<p>For each human gene, the expected number of mutations is obtained based on the normal mutation pa...
© 2013 Dr. Sally Jayne DavisGenomic copy number amplification is a hallmark of oncogene-associated t...
<p>Genes that are known to be associated with cancer (black) and all remaining genes (gray) were gro...
Ovarian cancer is a disease characterised by complex genomic rearrangements but the majority of the ...
Ovarian cancer is a disease characterised by complex genomic rearrangements but the majority of the ...
Amplification of 8p11-12 is a well-known alteration in human breast cancers but the driving oncogene...
<p>Top 10 genes that showed the highest amount of overexpression in FTO-4 mice per tissue.</p
Chromosome region 17q12-23 commonly shows an increase in DNA copy number in breast cancers, suggesti...
<p>Percentages are the proportion of tumors having a mutation within a subtype, e.g. 37% of Bronchio...
Gene amplification was recognized as a physiological process during the development of Drosophila me...
Imbalanced expression of somatic alleles in cancer can suggest functional and selective features, an...
Dominant functional categories (rows) enriched in the large list of 5602 genes (columns) having incr...