Mean DNA methylation levels for hypermethylated genes sorted by group.

<p><b>A.</b> Genes commonly methylated in >95% of all samples.</p><p><b>B.</b> Genes methylated in all tumorous samples (including MCRC).</p><p><b>C.</b> Genes methylated only in LGD, HGD and stage I-III CRC.</p><p><b>D.</b> Genes individually methylated in certain groups.</p><p>Y: young normal, N: adult normal, CN: macroscopically normal tissue taken from at least 10 cm away from the tumor margin, F: macroscopically normal tissue taken from 1 cm away from the tumor margin, LGD: low-grade dysplasia, HGD: high-grade dysplasia, CRC: colorectal cancer, MCRC: metastatic CRC, UCi: inactive ulcerative colitis, UCa: active ulcerative colitis. Bold: genes hypermethylated in more than half of the samples in the representative group.</p><p>Mean DNA methylation levels for hypermethylated genes sorted by group.