<p>A. The PI3K inhibitor LY294002 and (B) the MEK1 inhibitor PD98059 (10 and 50 μM) were added to neutrophils for 30 minutes before stimulating the cells with opsonised <i>E. coli</i>. After 90 minutes the activation of Mac-1 was assessed by flow cytometry. Unstimulated and control <i>E. coli</i> stimulated samples were incubated with the highest concentration of carrier (DMSO) used. Data are mean ± SEM (n = 6). ** indicates p<0.01, *** p<0.001.</p
<p>(<b>a</b>) PI3 kinase activity was measured in non-diabetic CD34<sup>+</sup> cells by measuring t...
<p>(<b>A</b>) PI3K inhibitor LY294002 (LY) decreases doxorubicin efflux in cell lines 10B and A549. ...
<p>Neutrophils were treated with 1μM and 10μM of the PI3Kδ selective inhibitor PIK-274 for 30 mins p...
<p>(A) Cell spreading assay of MDCK+CADM1-GFP cells incubated on IgG or CADM1-EC-Fc in the presence ...
<p>The cells were transfected with miR-223 inhibitor or its control and were sensitized with anti-DN...
<p>(A) Pretreatment of neutrophils with wortmannin (100 nM, 30 min; <i>solid bars</i>) inhibited bot...
<p><b>A.</b> Human neutrophils were incubated in IMDM +10% autologous serum in the presence (closed ...
<p><b>A.</b> Global inhibition of the PI3K kinase pathway with LY294002 significantly increases macr...
<p>The indicated MCC and melanoma cell lines were incubated with LY-294002 at three different concen...
<p>Luminex profiling of MMPs, cytokines, chemokines and growth factors demonstrates that Mtb infecti...
Full length adiponectin is a potent immune modulatory adipokine, impacting upon the actions of sever...
<p>a) Neutrophils were pre-treated for 30 mins with varying concentrations (from 0.1μM to 10μM) of t...
<p>Representative immunoblots of RAW cells (A) and murine peritoneal macrophages (B) pretreated with...
<p><b>A & B:</b> CD40, but not Mac-1, is required for sCD40L- stimulated neutrophil oxidative burst....
<p>BEAS-2B cells were left uninfected (A, D); or infected with RV-1B (B, E) or RV-16 (C, F) at 1×10<...
<p>(<b>a</b>) PI3 kinase activity was measured in non-diabetic CD34<sup>+</sup> cells by measuring t...
<p>(<b>A</b>) PI3K inhibitor LY294002 (LY) decreases doxorubicin efflux in cell lines 10B and A549. ...
<p>Neutrophils were treated with 1μM and 10μM of the PI3Kδ selective inhibitor PIK-274 for 30 mins p...
<p>(A) Cell spreading assay of MDCK+CADM1-GFP cells incubated on IgG or CADM1-EC-Fc in the presence ...
<p>The cells were transfected with miR-223 inhibitor or its control and were sensitized with anti-DN...
<p>(A) Pretreatment of neutrophils with wortmannin (100 nM, 30 min; <i>solid bars</i>) inhibited bot...
<p><b>A.</b> Human neutrophils were incubated in IMDM +10% autologous serum in the presence (closed ...
<p><b>A.</b> Global inhibition of the PI3K kinase pathway with LY294002 significantly increases macr...
<p>The indicated MCC and melanoma cell lines were incubated with LY-294002 at three different concen...
<p>Luminex profiling of MMPs, cytokines, chemokines and growth factors demonstrates that Mtb infecti...
Full length adiponectin is a potent immune modulatory adipokine, impacting upon the actions of sever...
<p>a) Neutrophils were pre-treated for 30 mins with varying concentrations (from 0.1μM to 10μM) of t...
<p>Representative immunoblots of RAW cells (A) and murine peritoneal macrophages (B) pretreated with...
<p><b>A & B:</b> CD40, but not Mac-1, is required for sCD40L- stimulated neutrophil oxidative burst....
<p>BEAS-2B cells were left uninfected (A, D); or infected with RV-1B (B, E) or RV-16 (C, F) at 1×10<...
<p>(<b>a</b>) PI3 kinase activity was measured in non-diabetic CD34<sup>+</sup> cells by measuring t...
<p>(<b>A</b>) PI3K inhibitor LY294002 (LY) decreases doxorubicin efflux in cell lines 10B and A549. ...
<p>Neutrophils were treated with 1μM and 10μM of the PI3Kδ selective inhibitor PIK-274 for 30 mins p...
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