PI3K-inhibitor (LY294002) decreases degranulation.

<p>The cells were transfected with miR-223 inhibitor or its control and were sensitized with anti-DNP IgE overnight. The cells were then triggered with DNP-HSA with or without LY294002. After triggering for 1 h, release of β-hexosaminidase were detected in four groups. Data are represented as the mean ± SD for three experiments (n = 6). *<i>P</i> < 0.01 compared to the control group; ^#<i>P</i> < 0.01 compared to the miR-223 inhibitor group.