Differentiating CGP cells show a decline of HDAC activity and protein level.

<p>A, Immunoblot of CGP cells differentiating in vitro. CGP cells isolated from P5 wild type mice were plated and harvested at different days of in vitro culture (DIV). Numbers below immunoblots are the intensity normalized to undifferentiated cells. B, HDAC activity of CGP cells differentiated in vitro was measured. Assay was performed three times in triplicate and the representative one is shown. Bars correspond to mean ± S.E. of three independent experiments.