<p>Time-course of mean mRNA number showing different decay rates in different parameter regimes. Each curve is the average of 100 Gillespie simulations with the same initial conditions starting at steady state of the unregulated model (). Parameters same as <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0072676#pone-0072676-g001" target="_blank">Figure 1</a> with .</p
<p>A, mRNA and protein levels estimated by the structured covariance model (cf. <a href="http://www....
<p>Upper panel: R protein degradation rate (and other parameters as described in the text) with the...
<p>A. For transcripts for which stability values at each growth rate were available. B. For the 486 ...
<p>Time-course of mean mRNA number (first species) while transcription rate and interaction rate of ...
<p>Relative mRNA number as a function of the time after the interruption of transcription. (A) Two...
<p>Panel (a) shows the exponential lifetime density (red) defined in (1) and the gamma density wit...
(A) Clustering of pre-mRNA (Ai) and mature (Aii) mRNA time series. Plots show the mean expression va...
<p>During its lifetime, each mRNA undergoes biochemical modifications described by transitions from ...
<p>The relative mRNA number defined in Eq. (1) can be measured at different time points after the i...
<p>For each group, the histogram shows the mean value ± standard error of the half-lives of mRNAs -e...
<p>The lifetime distribution of an mRNA can be translated into an age-dependent degradation rate vi...
<p>The patterns are obtained from a systematic fitting procedure applying Eqs. (1) and (9) or (10) t...
<p>Dependence of the period (<i>τ</i>) on: the maximum rate of <i>per</i> mRNA synthesis, <i>v<sub>s...
A general program was written which simulates radioactive labeling of RNA . The program was used to ...
AbstractMessenger RNA (mRNA) dynamics in single cells are often modeled as a memoryless birth-death ...
<p>A, mRNA and protein levels estimated by the structured covariance model (cf. <a href="http://www....
<p>Upper panel: R protein degradation rate (and other parameters as described in the text) with the...
<p>A. For transcripts for which stability values at each growth rate were available. B. For the 486 ...
<p>Time-course of mean mRNA number (first species) while transcription rate and interaction rate of ...
<p>Relative mRNA number as a function of the time after the interruption of transcription. (A) Two...
<p>Panel (a) shows the exponential lifetime density (red) defined in (1) and the gamma density wit...
(A) Clustering of pre-mRNA (Ai) and mature (Aii) mRNA time series. Plots show the mean expression va...
<p>During its lifetime, each mRNA undergoes biochemical modifications described by transitions from ...
<p>The relative mRNA number defined in Eq. (1) can be measured at different time points after the i...
<p>For each group, the histogram shows the mean value ± standard error of the half-lives of mRNAs -e...
<p>The lifetime distribution of an mRNA can be translated into an age-dependent degradation rate vi...
<p>The patterns are obtained from a systematic fitting procedure applying Eqs. (1) and (9) or (10) t...
<p>Dependence of the period (<i>τ</i>) on: the maximum rate of <i>per</i> mRNA synthesis, <i>v<sub>s...
A general program was written which simulates radioactive labeling of RNA . The program was used to ...
AbstractMessenger RNA (mRNA) dynamics in single cells are often modeled as a memoryless birth-death ...
<p>A, mRNA and protein levels estimated by the structured covariance model (cf. <a href="http://www....
<p>Upper panel: R protein degradation rate (and other parameters as described in the text) with the...
<p>A. For transcripts for which stability values at each growth rate were available. B. For the 486 ...
DOI
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