<p>Time-course of mean mRNA number (first species) while transcription rate and interaction rate of the other species is being changed. Each curve is the average of 100 Gillespie simulations with the same initial conditions at steady state of unregulated system (). For both species parameters are the same as <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0072676#pone-0072676-g001" target="_blank">Figure 1</a> with with the exception of the parameter under study. <b>A)</b> Time course of mRNA as transcritption rate of the competing mRNA is changed. <b>B)</b> Time course of mRNA as interaction rate of the competing mRNA is changed.</p
Broader comprehension of gene expression regulatory mechanisms can be gained from a global analysis ...
AbstractRegulation of mRNA decay is a critical component of global cellular adaptation to changing e...
<p>(A–C) Steady state value for means, Fano factors and coefficients of variation for each free mole...
<p>Time-course of mean mRNA number showing different decay rates in different parameter regimes. Eac...
<p><b>A)</b> Schematic of mRNA crosstalk through a shared pool of microRNAs. stand for transcriptio...
International audienceIn living organisms, the same enzyme catalyses the degradation of thousands of...
<p>Concentrations of sRNA, mRNA, mRNA-sRNA complex, competitor mRNA, complex formed by competitor mR...
A kinetic-dynamic model was proposed to simulate RNA processing by determining four essential reacti...
<p>Relative mRNA number as a function of the time after the interruption of transcription. (A) Two...
In cells, genes are transcribed into mRNAs, and the latter are translated into proteins. Due to the ...
The experiments indicate that the transcription of genes into ncRNA can positively or negatively int...
(A) Clustering of pre-mRNA (Ai) and mature (Aii) mRNA time series. Plots show the mean expression va...
<p>Figure showing the percentage of difference between LNA results and Gillespie results in the ceRN...
Although mRNA decay rates are a key determinant of the steady-state concentration for any given mRNA...
Although mRNA decay rates are a key determinant of the steady-state concentration for any given mRNA...
Broader comprehension of gene expression regulatory mechanisms can be gained from a global analysis ...
AbstractRegulation of mRNA decay is a critical component of global cellular adaptation to changing e...
<p>(A–C) Steady state value for means, Fano factors and coefficients of variation for each free mole...
<p>Time-course of mean mRNA number showing different decay rates in different parameter regimes. Eac...
<p><b>A)</b> Schematic of mRNA crosstalk through a shared pool of microRNAs. stand for transcriptio...
International audienceIn living organisms, the same enzyme catalyses the degradation of thousands of...
<p>Concentrations of sRNA, mRNA, mRNA-sRNA complex, competitor mRNA, complex formed by competitor mR...
A kinetic-dynamic model was proposed to simulate RNA processing by determining four essential reacti...
<p>Relative mRNA number as a function of the time after the interruption of transcription. (A) Two...
In cells, genes are transcribed into mRNAs, and the latter are translated into proteins. Due to the ...
The experiments indicate that the transcription of genes into ncRNA can positively or negatively int...
(A) Clustering of pre-mRNA (Ai) and mature (Aii) mRNA time series. Plots show the mean expression va...
<p>Figure showing the percentage of difference between LNA results and Gillespie results in the ceRN...
Although mRNA decay rates are a key determinant of the steady-state concentration for any given mRNA...
Although mRNA decay rates are a key determinant of the steady-state concentration for any given mRNA...
Broader comprehension of gene expression regulatory mechanisms can be gained from a global analysis ...
AbstractRegulation of mRNA decay is a critical component of global cellular adaptation to changing e...
<p>(A–C) Steady state value for means, Fano factors and coefficients of variation for each free mole...