<p>A. For transcripts for which stability values at each growth rate were available. B. For the 486 transcripts with half-lives values available for all three growth rates. The darker the histogram, the higher is the growth rate: black for µ = 0.80 h<sup>−1</sup>, dark gray for µ = 0.51 h<sup>−1</sup> and light gray for µ = 0.11 h<sup>−1</sup>. Half-lives are in reported in minutes. The lines are the rolling averages and thus represent the overall tendency of the data.</p
(A) Clustering of pre-mRNA (Ai) and mature (Aii) mRNA time series. Plots show the mean expression va...
(A) Reads aligned to intronic and exonic regions of genes are used to represent pre-mRNA (blue) and ...
Four example genes were chosen to demonstrate the range of half-lives that can be measured in this e...
<p>Half-life distributions of the genes from the bottom <i>20%</i> RD (green curve), top <i>20%</i> ...
<p>For each group, the histogram shows the mean value ± standard error of the half-lives of mRNAs -e...
<p>X axis: growth rate; Y axis: average half-life; Error bars represent the 5% confidence interval.<...
(A) Graph showing the correlation between mRNA half-life and 3′ UTR length. Data fit with linear reg...
<p>Half-life of mRNA at each time point was determined by real-time RT-PCR. *decay rate was too low ...
<p>Relative mRNA number as a function of the time after the interruption of transcription. (A) Two...
<p>(A) The half-lives of 26 Tis11-sensitive and control mRNAs, as measured by qPCR in SL2 cells subj...
<p>Actinomycin D (Act D) mRNA decay of B<sub>1</sub>R WT and SV transcripts in H2126 measured at 0, ...
A general program was written which simulates radioactive labeling of RNA . The program was used to ...
<p>The red lines represent from Eq. (6) when the lifetime density is exponential and is given by Eq...
(A) Parameter estimates for degradation rates and credible regions of short and long half-life mRNAs...
<p>Panel (a) shows the exponential lifetime density (red) defined in (1) and the gamma density wit...
(A) Clustering of pre-mRNA (Ai) and mature (Aii) mRNA time series. Plots show the mean expression va...
(A) Reads aligned to intronic and exonic regions of genes are used to represent pre-mRNA (blue) and ...
Four example genes were chosen to demonstrate the range of half-lives that can be measured in this e...
<p>Half-life distributions of the genes from the bottom <i>20%</i> RD (green curve), top <i>20%</i> ...
<p>For each group, the histogram shows the mean value ± standard error of the half-lives of mRNAs -e...
<p>X axis: growth rate; Y axis: average half-life; Error bars represent the 5% confidence interval.<...
(A) Graph showing the correlation between mRNA half-life and 3′ UTR length. Data fit with linear reg...
<p>Half-life of mRNA at each time point was determined by real-time RT-PCR. *decay rate was too low ...
<p>Relative mRNA number as a function of the time after the interruption of transcription. (A) Two...
<p>(A) The half-lives of 26 Tis11-sensitive and control mRNAs, as measured by qPCR in SL2 cells subj...
<p>Actinomycin D (Act D) mRNA decay of B<sub>1</sub>R WT and SV transcripts in H2126 measured at 0, ...
A general program was written which simulates radioactive labeling of RNA . The program was used to ...
<p>The red lines represent from Eq. (6) when the lifetime density is exponential and is given by Eq...
(A) Parameter estimates for degradation rates and credible regions of short and long half-life mRNAs...
<p>Panel (a) shows the exponential lifetime density (red) defined in (1) and the gamma density wit...
(A) Clustering of pre-mRNA (Ai) and mature (Aii) mRNA time series. Plots show the mean expression va...
(A) Reads aligned to intronic and exonic regions of genes are used to represent pre-mRNA (blue) and ...
Four example genes were chosen to demonstrate the range of half-lives that can be measured in this e...